Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalyst
Abstract The rational design of robust nanocatalysts containing the suitable active sites for building relevant organic compounds, such as lactams, is a desired approximation towards the development of a sustainable fine chemistry field. In that sense, the design of a proper nanomaterial able to med...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-59514-7 |
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| author | Carles Lluna-Galán Juan Camilo Arango-Daza Daviel Gómez Patricia Concepción Rong Sun Jose J. Calvino Laura Simonelli Rosa Adam Jose R. Cabrero-Antonino |
| author_facet | Carles Lluna-Galán Juan Camilo Arango-Daza Daviel Gómez Patricia Concepción Rong Sun Jose J. Calvino Laura Simonelli Rosa Adam Jose R. Cabrero-Antonino |
| author_sort | Carles Lluna-Galán |
| collection | DOAJ |
| description | Abstract The rational design of robust nanocatalysts containing the suitable active sites for building relevant organic compounds, such as lactams, is a desired approximation towards the development of a sustainable fine chemistry field. In that sense, the design of a proper nanomaterial able to mediate the selective hydrodeoxygenation of cyclic imides to lactams with high tolerance to the preservation of aromatic rings remains rather unexplored. Here, we show the design of a bimetallic AgRe nanomaterial with notable activity and selectivity to mediate this transformation affording more than 60 lactams from the corresponding imides. Interestingly, in this work we disclose that the optimal AgRe nanocatalyst is constituted by AgReO4 nanoaggregates that undergo an in situ hydrogenative dispersion to form the active centers composed by Ag0 nanoparticles and ReOx species. Deep characterization, together with kinetic and mechanistic studies, have revealed that the intimate Ag-Re contact intrinsic to AgReO4 species is key for the formation of the most active catalytic sites and the proper bimetallic cooperation required for mediating the desired process. |
| format | Article |
| id | doaj-art-48ef77079dd4485bb94b1a2608c3ef72 |
| institution | OA Journals |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-48ef77079dd4485bb94b1a2608c3ef722025-08-20T02:10:50ZengNature PortfolioNature Communications2041-17232025-05-0116112510.1038/s41467-025-59514-7Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalystCarles Lluna-Galán0Juan Camilo Arango-Daza1Daviel Gómez2Patricia Concepción3Rong Sun4Jose J. Calvino5Laura Simonelli6Rosa Adam7Jose R. Cabrero-Antonino8Instituto de Tecnología Química. Universitat Politècnica de València-Consejo Superior Investigaciones Científicas (UPV-CSIC). Avda. de los Naranjos s/nInstituto de Tecnología Química. Universitat Politècnica de València-Consejo Superior Investigaciones Científicas (UPV-CSIC). Avda. de los Naranjos s/nInstituto de Tecnología Química. Universitat Politècnica de València-Consejo Superior Investigaciones Científicas (UPV-CSIC). Avda. de los Naranjos s/nInstituto de Tecnología Química. Universitat Politècnica de València-Consejo Superior Investigaciones Científicas (UPV-CSIC). Avda. de los Naranjos s/nDepartamento de Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica, Facultad de Ciencias, Universidad de Cádiz. Puerto RealDepartamento de Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica, Facultad de Ciencias, Universidad de Cádiz. Puerto RealCELLS-ALBA Synchrotron Radiation Facility. Cerdanyola del VallèsDepartament de Química Orgànica, Facultat de Farmàcia, Universitat de València, Av. Vicent Andrés Estellés s/n, BurjassotInstituto de Tecnología Química. Universitat Politècnica de València-Consejo Superior Investigaciones Científicas (UPV-CSIC). Avda. de los Naranjos s/nAbstract The rational design of robust nanocatalysts containing the suitable active sites for building relevant organic compounds, such as lactams, is a desired approximation towards the development of a sustainable fine chemistry field. In that sense, the design of a proper nanomaterial able to mediate the selective hydrodeoxygenation of cyclic imides to lactams with high tolerance to the preservation of aromatic rings remains rather unexplored. Here, we show the design of a bimetallic AgRe nanomaterial with notable activity and selectivity to mediate this transformation affording more than 60 lactams from the corresponding imides. Interestingly, in this work we disclose that the optimal AgRe nanocatalyst is constituted by AgReO4 nanoaggregates that undergo an in situ hydrogenative dispersion to form the active centers composed by Ag0 nanoparticles and ReOx species. Deep characterization, together with kinetic and mechanistic studies, have revealed that the intimate Ag-Re contact intrinsic to AgReO4 species is key for the formation of the most active catalytic sites and the proper bimetallic cooperation required for mediating the desired process.https://doi.org/10.1038/s41467-025-59514-7 |
| spellingShingle | Carles Lluna-Galán Juan Camilo Arango-Daza Daviel Gómez Patricia Concepción Rong Sun Jose J. Calvino Laura Simonelli Rosa Adam Jose R. Cabrero-Antonino Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalyst Nature Communications |
| title | Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalyst |
| title_full | Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalyst |
| title_fullStr | Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalyst |
| title_full_unstemmed | Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalyst |
| title_short | Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalyst |
| title_sort | building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina supported agre bimetallic nanocatalyst |
| url | https://doi.org/10.1038/s41467-025-59514-7 |
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