Strongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearing

Abstract Optical imaging plays a central role in the field of biomedicine, but it suffers from the light scattering of tissues. The research group from Stanford University has reported a counterintuitive observation that strongly absorbing molecules could achieve optical transparency in live animals...

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Bibliographic Details
Main Authors: Tingting Yu, Dan Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-024-01675-z
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Summary:Abstract Optical imaging plays a central role in the field of biomedicine, but it suffers from the light scattering of tissues. The research group from Stanford University has reported a counterintuitive observation that strongly absorbing molecules could achieve optical transparency in live animals, providing a new insight for understanding tissue optical clearing. It empowers scientists to leverage optical imaging techniques for in vivo observation of a wide range of deep-seated structures and activities.
ISSN:2047-7538