ATTEMPT OF OVERCOMING SECONDARY INEFFECTIVENESS OF INFLIXIMAB IN A PATIENT WITH ANKYLOSING SPONDYLITIS USING PLASMAPHERESIS (A CASE REPORT)

The article focuses on the problem of secondary ineffectiveness of tumor necrosis factor α infliximab (INF) and describes an attempt of using plasmapheresis (PF) to eliminate this problem in a patient with ankylosing spondylitis who had received INF treatment at a dose of 5 mg/kg for a long time (ov...

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Main Authors: Oksana Alekseyevna Rumyantseva, A G Bochkova, S K Soloviev, Sh F Erdes
Format: Article
Language:Russian
Published: IMA PRESS LLC 2014-02-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/1687
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author Oksana Alekseyevna Rumyantseva
A G Bochkova
S K Soloviev
Sh F Erdes
author_facet Oksana Alekseyevna Rumyantseva
A G Bochkova
S K Soloviev
Sh F Erdes
author_sort Oksana Alekseyevna Rumyantseva
collection DOAJ
description The article focuses on the problem of secondary ineffectiveness of tumor necrosis factor α infliximab (INF) and describes an attempt of using plasmapheresis (PF) to eliminate this problem in a patient with ankylosing spondylitis who had received INF treatment at a dose of 5 mg/kg for a long time (over 4 years). After PF, the IFF therapy ensured a long-term clinical and laboratory improvement of patient's condition. One can assume that PF made it possible to overcome secondary ineffectiveness of INF and can be used in some patients in cases when INF cannot be replaced with another TNFα inhibitor.
format Article
id doaj-art-48e8a7fb21314eeea09ecd1462af5131
institution Kabale University
issn 1995-4484
1995-4492
language Russian
publishDate 2014-02-01
publisher IMA PRESS LLC
record_format Article
series Научно-практическая ревматология
spelling doaj-art-48e8a7fb21314eeea09ecd1462af51312025-08-20T03:38:11ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922014-02-01516725810.14412/1995-4484-2013-725-81624ATTEMPT OF OVERCOMING SECONDARY INEFFECTIVENESS OF INFLIXIMAB IN A PATIENT WITH ANKYLOSING SPONDYLITIS USING PLASMAPHERESIS (A CASE REPORT)Oksana Alekseyevna Rumyantseva0A G Bochkova1S K Soloviev2Sh F Erdes3Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, RussiaNasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, RussiaNasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, RussiaNasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, RussiaThe article focuses on the problem of secondary ineffectiveness of tumor necrosis factor α infliximab (INF) and describes an attempt of using plasmapheresis (PF) to eliminate this problem in a patient with ankylosing spondylitis who had received INF treatment at a dose of 5 mg/kg for a long time (over 4 years). After PF, the IFF therapy ensured a long-term clinical and laboratory improvement of patient's condition. One can assume that PF made it possible to overcome secondary ineffectiveness of INF and can be used in some patients in cases when INF cannot be replaced with another TNFα inhibitor.https://rsp.mediar-press.net/rsp/article/view/1687infliximabplasmapheresisankylosing spondylitis
spellingShingle Oksana Alekseyevna Rumyantseva
A G Bochkova
S K Soloviev
Sh F Erdes
ATTEMPT OF OVERCOMING SECONDARY INEFFECTIVENESS OF INFLIXIMAB IN A PATIENT WITH ANKYLOSING SPONDYLITIS USING PLASMAPHERESIS (A CASE REPORT)
Научно-практическая ревматология
infliximab
plasmapheresis
ankylosing spondylitis
title ATTEMPT OF OVERCOMING SECONDARY INEFFECTIVENESS OF INFLIXIMAB IN A PATIENT WITH ANKYLOSING SPONDYLITIS USING PLASMAPHERESIS (A CASE REPORT)
title_full ATTEMPT OF OVERCOMING SECONDARY INEFFECTIVENESS OF INFLIXIMAB IN A PATIENT WITH ANKYLOSING SPONDYLITIS USING PLASMAPHERESIS (A CASE REPORT)
title_fullStr ATTEMPT OF OVERCOMING SECONDARY INEFFECTIVENESS OF INFLIXIMAB IN A PATIENT WITH ANKYLOSING SPONDYLITIS USING PLASMAPHERESIS (A CASE REPORT)
title_full_unstemmed ATTEMPT OF OVERCOMING SECONDARY INEFFECTIVENESS OF INFLIXIMAB IN A PATIENT WITH ANKYLOSING SPONDYLITIS USING PLASMAPHERESIS (A CASE REPORT)
title_short ATTEMPT OF OVERCOMING SECONDARY INEFFECTIVENESS OF INFLIXIMAB IN A PATIENT WITH ANKYLOSING SPONDYLITIS USING PLASMAPHERESIS (A CASE REPORT)
title_sort attempt of overcoming secondary ineffectiveness of infliximab in a patient with ankylosing spondylitis using plasmapheresis a case report
topic infliximab
plasmapheresis
ankylosing spondylitis
url https://rsp.mediar-press.net/rsp/article/view/1687
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AT agbochkova attemptofovercomingsecondaryineffectivenessofinfliximabinapatientwithankylosingspondylitisusingplasmapheresisacasereport
AT sksoloviev attemptofovercomingsecondaryineffectivenessofinfliximabinapatientwithankylosingspondylitisusingplasmapheresisacasereport
AT shferdes attemptofovercomingsecondaryineffectivenessofinfliximabinapatientwithankylosingspondylitisusingplasmapheresisacasereport