Randomized controlled trial evaluating the benefit of the app-based clinical decision support system for the management of venous thromboembolism

Abstract Introduction Anticoagulant prescription and management are crucial steps of management of venous thromboembolism (VTE). The Clinical decision support systems (CDSS) are designed and developed to aid healthcare professionals in making informed decisions. Objectives To develop and assess the...

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Main Authors: Pajaree Chairat, Piangrawee Niprapan, Nonthakorn Hantrakun, Adisak Tantiworawit, Teerachat Punnachet, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Ekarat Rattarittamrong, Lalita Norasetthada, Chatree Chai-Adisaksopha
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Medical Education
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Online Access:https://doi.org/10.1186/s12909-025-07014-z
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author Pajaree Chairat
Piangrawee Niprapan
Nonthakorn Hantrakun
Adisak Tantiworawit
Teerachat Punnachet
Pokpong Piriyakhuntorn
Thanawat Rattanathammethee
Sasinee Hantrakool
Ekarat Rattarittamrong
Lalita Norasetthada
Chatree Chai-Adisaksopha
author_facet Pajaree Chairat
Piangrawee Niprapan
Nonthakorn Hantrakun
Adisak Tantiworawit
Teerachat Punnachet
Pokpong Piriyakhuntorn
Thanawat Rattanathammethee
Sasinee Hantrakool
Ekarat Rattarittamrong
Lalita Norasetthada
Chatree Chai-Adisaksopha
author_sort Pajaree Chairat
collection DOAJ
description Abstract Introduction Anticoagulant prescription and management are crucial steps of management of venous thromboembolism (VTE). The Clinical decision support systems (CDSS) are designed and developed to aid healthcare professionals in making informed decisions. Objectives To develop and assess the efficacy the mobile app-based CDSS for the management of VTE. Methods A randomized controlled trial was conducted, enrolling participants aged ≥ 20 years who were one of the following categories: medical student, intern, internal medicine resident, or hematology fellow. Participants were randomly assigned to either app-based CDSS (DECIDE-COAG®) or control groups. Participants were tasked with prescribing or planning the management of 15 clinical vignettes covering four domains: anticoagulant dosing, perioperative management, management of anticoagulant associated bleeding and diagnosis of VTE. The primary outcome was the mean percentage of accuracy score. Results From September 2023 through November 2023, a total of 126 participants were enrolled. The mean percentage of accuracy score was significantly higher (95.6%) in participants using app-based CDSS compared with those in control group (41.3%), a mean difference of 54.5%, 95% CI 49.8–59.2, p < 0.001. The satisfaction mean score was 4.57 ± 0.49 for accessibility, 4.73 ± 0.45 for app stability, 4.94 ± 0.25 for user interface, 4.78 ± 0.42 for simplicity, 4.98 ± 0.13 for assistance in decision-making and 4.90 ± 0.30 for overall satisfaction. Conclusions App-based CDSS (DECIDE-COAG®) demonstrates a significant improvement in the accuracy of anticoagulant prescriptions and VTE management. Further studies that specifically investigate the clinical benefits of app-based CDSS in real-world clinical practice are warranted. Clinical trial number TCTR20241117004.
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spelling doaj-art-48cf52b488f2468c8072d77f761092b72025-08-20T01:56:06ZengBMCBMC Medical Education1472-69202025-03-012511810.1186/s12909-025-07014-zRandomized controlled trial evaluating the benefit of the app-based clinical decision support system for the management of venous thromboembolismPajaree Chairat0Piangrawee Niprapan1Nonthakorn Hantrakun2Adisak Tantiworawit3Teerachat Punnachet4Pokpong Piriyakhuntorn5Thanawat Rattanathammethee6Sasinee Hantrakool7Ekarat Rattarittamrong8Lalita Norasetthada9Chatree Chai-Adisaksopha10Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityAbstract Introduction Anticoagulant prescription and management are crucial steps of management of venous thromboembolism (VTE). The Clinical decision support systems (CDSS) are designed and developed to aid healthcare professionals in making informed decisions. Objectives To develop and assess the efficacy the mobile app-based CDSS for the management of VTE. Methods A randomized controlled trial was conducted, enrolling participants aged ≥ 20 years who were one of the following categories: medical student, intern, internal medicine resident, or hematology fellow. Participants were randomly assigned to either app-based CDSS (DECIDE-COAG®) or control groups. Participants were tasked with prescribing or planning the management of 15 clinical vignettes covering four domains: anticoagulant dosing, perioperative management, management of anticoagulant associated bleeding and diagnosis of VTE. The primary outcome was the mean percentage of accuracy score. Results From September 2023 through November 2023, a total of 126 participants were enrolled. The mean percentage of accuracy score was significantly higher (95.6%) in participants using app-based CDSS compared with those in control group (41.3%), a mean difference of 54.5%, 95% CI 49.8–59.2, p < 0.001. The satisfaction mean score was 4.57 ± 0.49 for accessibility, 4.73 ± 0.45 for app stability, 4.94 ± 0.25 for user interface, 4.78 ± 0.42 for simplicity, 4.98 ± 0.13 for assistance in decision-making and 4.90 ± 0.30 for overall satisfaction. Conclusions App-based CDSS (DECIDE-COAG®) demonstrates a significant improvement in the accuracy of anticoagulant prescriptions and VTE management. Further studies that specifically investigate the clinical benefits of app-based CDSS in real-world clinical practice are warranted. Clinical trial number TCTR20241117004.https://doi.org/10.1186/s12909-025-07014-zVenous thromboembolismCDSSAnticoagulantPrescription errorWarfarin
spellingShingle Pajaree Chairat
Piangrawee Niprapan
Nonthakorn Hantrakun
Adisak Tantiworawit
Teerachat Punnachet
Pokpong Piriyakhuntorn
Thanawat Rattanathammethee
Sasinee Hantrakool
Ekarat Rattarittamrong
Lalita Norasetthada
Chatree Chai-Adisaksopha
Randomized controlled trial evaluating the benefit of the app-based clinical decision support system for the management of venous thromboembolism
BMC Medical Education
Venous thromboembolism
CDSS
Anticoagulant
Prescription error
Warfarin
title Randomized controlled trial evaluating the benefit of the app-based clinical decision support system for the management of venous thromboembolism
title_full Randomized controlled trial evaluating the benefit of the app-based clinical decision support system for the management of venous thromboembolism
title_fullStr Randomized controlled trial evaluating the benefit of the app-based clinical decision support system for the management of venous thromboembolism
title_full_unstemmed Randomized controlled trial evaluating the benefit of the app-based clinical decision support system for the management of venous thromboembolism
title_short Randomized controlled trial evaluating the benefit of the app-based clinical decision support system for the management of venous thromboembolism
title_sort randomized controlled trial evaluating the benefit of the app based clinical decision support system for the management of venous thromboembolism
topic Venous thromboembolism
CDSS
Anticoagulant
Prescription error
Warfarin
url https://doi.org/10.1186/s12909-025-07014-z
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