Automatic Detection of Radiographic Alveolar Bone Loss in Bitewing and Periapical Intraoral Radiographs Using Deep Learning Technology: A Preliminary Evaluation

<b>Background/Objective:</b> Periodontal disease is a prevalent inflammatory condition affecting the supporting structures of teeth, with radiographic bone loss (RBL) being a critical diagnostic marker. The accurate and consistent evaluation of RBL is essential for the staging and gradin...

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Main Authors: Amjad AlGhaihab, Antonio J. Moretti, Jonathan Reside, Lyudmila Tuzova, Yiing-Shiuan Huang, Donald A. Tyndall
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/5/576
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Summary:<b>Background/Objective:</b> Periodontal disease is a prevalent inflammatory condition affecting the supporting structures of teeth, with radiographic bone loss (RBL) being a critical diagnostic marker. The accurate and consistent evaluation of RBL is essential for the staging and grading of periodontitis, as outlined by the 2017 AAP/EFP Classification. Advanced tools such as deep learning (DL) technology, including Denti.AI, an FDA-cleared software utilizing convolutional neural networks (CNNs), offer the potential for enhancing diagnostic accuracy. This study evaluated the diagnostic accuracy of Denti.AI for detecting RBL in intraoral radiographs. <b>Methods:</b> A dataset of 39 intraoral radiographs (22 periapical and 17 bitewing), covering 316 tooth surfaces (123 periapical and 193 bitewing), was selected from a de-identified pool of 500 radiographs provided by Denti.AI. RBL was assessed using the 2017 AAP/EFP Classification. A consensus panel of three board-certified dental specialists served as the reference standard. Performance metrics, including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and mean absolute error (MAE), were calculated. <b>Results:</b> For periapical radiographs, Denti.AI achieved a sensitivity of 76%, specificity of 86%, PPV of 83%, NPV of 80%, and accuracy of 81%, with an MAE of 0.046%. For bitewing radiographs, sensitivity was 65%, specificity was 90%, PPV was 88%, NPV was 70%, and accuracy was 76%, with an MAE of 0.499 mm. <b>Conclusions:</b> Denti.AI demonstrated clinically acceptable performance in detecting RBL and shows potential as an adjunctive diagnostic tool, supporting clinical decision-making. While performance was robust for periapical radiographs, further optimization may enhance its accuracy for bitewing radiographs.
ISSN:2075-4418