Tumor-associated macrophages correlate with better outcome in SHH medulloblastoma

Tumor-associated macrophages correlate with better outcome in SHH medulloblastoma

ObjectiveTumor-associated macrophages (TAMs) constitute a significant proportion of the immune cell population within brain tumors. The polarization of macrophages exerts an important influence on the tumor microenvironment (TME). Nevertheless, the specific role of TAMs in sonic hedgehog (SHH) medul...

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Bibliographic Details
Main Authors: Jin Zhang, Shuting Li, Yuan Wang, Jingjing Liu, Yan Liu, Xiaojun Gong, Yanling Sun, Liming Sun, Zhigang Li, Tianyou Wang, Shuxu Du, Wanshui Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
medulloblastoma
macrophage
phenotype
age
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1557313/full
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