Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis

ObjectivePrediction models, which estimate disease or outcome probabilities, are widely used in cancer research. This study aims to identify hotspots and future directions of cancer-related prediction models using bibliometrics.MethodsA comprehensive literature search was conducted in the Science Ci...

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Main Authors: Siyu Li, Wenrui Li, Xiaoxiao Wang, Wanyi Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1556521/full
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author Siyu Li
Wenrui Li
Xiaoxiao Wang
Wanyi Chen
author_facet Siyu Li
Wenrui Li
Xiaoxiao Wang
Wanyi Chen
author_sort Siyu Li
collection DOAJ
description ObjectivePrediction models, which estimate disease or outcome probabilities, are widely used in cancer research. This study aims to identify hotspots and future directions of cancer-related prediction models using bibliometrics.MethodsA comprehensive literature search was conducted in the Science Citation Index Expanded (SCIE) from the Web of Science Core Collection (WoSCC) up to November 15, 2024, focusing on cancer-related prediction models research. Co-occurrence analyses of countries, institutions, authors, journals, and keywords were conducted using VOSviewer 1.6.20. Additionally, keyword clustering, timeline visualization, and burst term analysis were performed with CiteSpace 6.3.ResultsA total of 1,661 records were retrieved from the SCIE. After deduplication and eligibility screening, 1,556 publications were included in the analysis. The bibliometric analysis revealed a consistent annual increase in cancer-related prediction model research, with China and the United States emerging as the leading contributors. The United States, England, and the Netherlands had the strongest collaborative networks. The most frequent keywords, excluding “prediction model” and “predictive model”, included nomogram (frequency=192), survival (191), risk (121), prognosis (112), breast cancer (103), carcinoma (93), validation (87), surgery (85), diagnosis (83), chemotherapy (80), and machine learning (77). Besides, the timeline view analysis indicated that the “#7 machine learning” cluster was experiencing vigorous growth.ConclusionCancer-related prediction models are rapidly advancing, especially in prognostic models. Emerging modeling techniques, such as neural networks and deep learning algorithms, are likely to play a pivotal role in current and future cancer-related prediction model research. Systematic reviews of cancer-related predictive models, which could help clinicians select the optimal model for specific clinical conditions may emerge as potential research directions in this field.
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spelling doaj-art-48c0d00dd2ce460f9a07628db7cb976b2025-08-20T03:33:22ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-07-011510.3389/fonc.2025.15565211556521Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysisSiyu LiWenrui LiXiaoxiao WangWanyi ChenObjectivePrediction models, which estimate disease or outcome probabilities, are widely used in cancer research. This study aims to identify hotspots and future directions of cancer-related prediction models using bibliometrics.MethodsA comprehensive literature search was conducted in the Science Citation Index Expanded (SCIE) from the Web of Science Core Collection (WoSCC) up to November 15, 2024, focusing on cancer-related prediction models research. Co-occurrence analyses of countries, institutions, authors, journals, and keywords were conducted using VOSviewer 1.6.20. Additionally, keyword clustering, timeline visualization, and burst term analysis were performed with CiteSpace 6.3.ResultsA total of 1,661 records were retrieved from the SCIE. After deduplication and eligibility screening, 1,556 publications were included in the analysis. The bibliometric analysis revealed a consistent annual increase in cancer-related prediction model research, with China and the United States emerging as the leading contributors. The United States, England, and the Netherlands had the strongest collaborative networks. The most frequent keywords, excluding “prediction model” and “predictive model”, included nomogram (frequency=192), survival (191), risk (121), prognosis (112), breast cancer (103), carcinoma (93), validation (87), surgery (85), diagnosis (83), chemotherapy (80), and machine learning (77). Besides, the timeline view analysis indicated that the “#7 machine learning” cluster was experiencing vigorous growth.ConclusionCancer-related prediction models are rapidly advancing, especially in prognostic models. Emerging modeling techniques, such as neural networks and deep learning algorithms, are likely to play a pivotal role in current and future cancer-related prediction model research. Systematic reviews of cancer-related predictive models, which could help clinicians select the optimal model for specific clinical conditions may emerge as potential research directions in this field.https://www.frontiersin.org/articles/10.3389/fonc.2025.1556521/fullcancerprediction modelsmachine learningbibliometricsvisualization analysishotspots and trends
spellingShingle Siyu Li
Wenrui Li
Xiaoxiao Wang
Wanyi Chen
Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis
Frontiers in Oncology
cancer
prediction models
machine learning
bibliometrics
visualization analysis
hotspots and trends
title Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis
title_full Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis
title_fullStr Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis
title_full_unstemmed Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis
title_short Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis
title_sort progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer related complications a bibliometric and visualization analysis
topic cancer
prediction models
machine learning
bibliometrics
visualization analysis
hotspots and trends
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1556521/full
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