Coronary Stenosis in Type 2 Diabetes: A Comparative Review of HbA1c, Lipid Profiles, Blood Pressure, and BMI
Coronary artery disease (CAD) remains a leading cause of morbidity and mortality globally, with Type 2 Diabetes Mellitus (T2DM) significantly exacerbating its progression and severity. Understanding the interplay between modifiable risk factors and the degree of coronary stenosis in T2DM patients is...
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| Format: | Article |
| Language: | English |
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Bucharest College of Physicians
2025-03-01
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| Series: | Modern Medicine |
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| Online Access: | https://medicinamoderna.ro/wp-content/uploads/2025/03/Coronary-Stenosis-in-Type-2-Diabetes-A-Comparative-Review-of-HbA1c-Lipid-Profiles-Blood-Press.pdf |
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| author | Shivankan KAKKAR Monica JAIN Jaya DADHICH Ayesha ARORA Nivedita GUPTA Jitendra Kumar GUPTA |
| author_facet | Shivankan KAKKAR Monica JAIN Jaya DADHICH Ayesha ARORA Nivedita GUPTA Jitendra Kumar GUPTA |
| author_sort | Shivankan KAKKAR |
| collection | DOAJ |
| description | Coronary artery disease (CAD) remains a leading cause of morbidity and mortality globally, with Type 2 Diabetes Mellitus (T2DM) significantly exacerbating its progression and severity. Understanding the interplay between modifiable risk factors and the degree of coronary stenosis in T2DM patients is crucial for optimized patient management and risk stratification. This review article critically evaluates the existing literature comparing the association of HbA1c, triglycerides, HDL cholesterol, blood pressure, and body mass index (BMI) with the degree of coronary stenosis in individuals with T2DM undergoing coronary angiography. We explore the pathophysiological mechanisms linking these factors to atherosclerosis and stenosis, analyze the evidence from observational and interventional studies, and discuss the relative strength and limitations of each marker in predicting and managing coronary stenosis in this high-risk population. Ultimately, this review aims to provide medical professionals with a comprehensive and nuanced understanding to guide clinical decision-making in the prevention and treatment of CAD in T2DM patients. |
| format | Article |
| id | doaj-art-48bbe8b272e14c5aa4398b842127f4bc |
| institution | DOAJ |
| issn | 1223-0472 2360-2473 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Bucharest College of Physicians |
| record_format | Article |
| series | Modern Medicine |
| spelling | doaj-art-48bbe8b272e14c5aa4398b842127f4bc2025-08-20T03:03:32ZengBucharest College of PhysiciansModern Medicine1223-04722360-24732025-03-01321535810.31689/rmm.2025.32.1.53Coronary Stenosis in Type 2 Diabetes: A Comparative Review of HbA1c, Lipid Profiles, Blood Pressure, and BMIShivankan KAKKAR0https://orcid.org/0000-0003-0290-2457Monica JAIN1Jaya DADHICH2Ayesha ARORA3Nivedita GUPTA4Jitendra Kumar GUPTA5SMS Medical College, Jaipur, Rajasthan, IndiaSMS Medical College, Jaipur, Rajasthan, IndiaSMS Medical College, Jaipur, Rajasthan, IndiaEDWARD HINES VA HOSPITAL, Chicago, IL, USASMS Medical College, Jaipur, Rajasthan, IndiaSMS Medical College, Jaipur, Rajasthan, IndiaCoronary artery disease (CAD) remains a leading cause of morbidity and mortality globally, with Type 2 Diabetes Mellitus (T2DM) significantly exacerbating its progression and severity. Understanding the interplay between modifiable risk factors and the degree of coronary stenosis in T2DM patients is crucial for optimized patient management and risk stratification. This review article critically evaluates the existing literature comparing the association of HbA1c, triglycerides, HDL cholesterol, blood pressure, and body mass index (BMI) with the degree of coronary stenosis in individuals with T2DM undergoing coronary angiography. We explore the pathophysiological mechanisms linking these factors to atherosclerosis and stenosis, analyze the evidence from observational and interventional studies, and discuss the relative strength and limitations of each marker in predicting and managing coronary stenosis in this high-risk population. Ultimately, this review aims to provide medical professionals with a comprehensive and nuanced understanding to guide clinical decision-making in the prevention and treatment of CAD in T2DM patients.https://medicinamoderna.ro/wp-content/uploads/2025/03/Coronary-Stenosis-in-Type-2-Diabetes-A-Comparative-Review-of-HbA1c-Lipid-Profiles-Blood-Press.pdfblood pressurecoronary artery disease (cad)hba1ctype 2 diabetes mellitus (t2dm) |
| spellingShingle | Shivankan KAKKAR Monica JAIN Jaya DADHICH Ayesha ARORA Nivedita GUPTA Jitendra Kumar GUPTA Coronary Stenosis in Type 2 Diabetes: A Comparative Review of HbA1c, Lipid Profiles, Blood Pressure, and BMI Modern Medicine blood pressure coronary artery disease (cad) hba1c type 2 diabetes mellitus (t2dm) |
| title | Coronary Stenosis in Type 2 Diabetes: A Comparative Review of HbA1c, Lipid Profiles, Blood Pressure, and BMI |
| title_full | Coronary Stenosis in Type 2 Diabetes: A Comparative Review of HbA1c, Lipid Profiles, Blood Pressure, and BMI |
| title_fullStr | Coronary Stenosis in Type 2 Diabetes: A Comparative Review of HbA1c, Lipid Profiles, Blood Pressure, and BMI |
| title_full_unstemmed | Coronary Stenosis in Type 2 Diabetes: A Comparative Review of HbA1c, Lipid Profiles, Blood Pressure, and BMI |
| title_short | Coronary Stenosis in Type 2 Diabetes: A Comparative Review of HbA1c, Lipid Profiles, Blood Pressure, and BMI |
| title_sort | coronary stenosis in type 2 diabetes a comparative review of hba1c lipid profiles blood pressure and bmi |
| topic | blood pressure coronary artery disease (cad) hba1c type 2 diabetes mellitus (t2dm) |
| url | https://medicinamoderna.ro/wp-content/uploads/2025/03/Coronary-Stenosis-in-Type-2-Diabetes-A-Comparative-Review-of-HbA1c-Lipid-Profiles-Blood-Press.pdf |
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