Clinical applications of nanoprobes of high-resolution in vivo imaging
Summary: Currently, the primary imaging methods used in clinical diagnosis are X-ray, computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), PET-CT, etc. The sensitivity and accuracy of these imaging methods bring many difficulties in clinical diagnosis; at the same time, CT, X-ray,...
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| Language: | English |
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Elsevier
2025-01-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224026865 |
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| author | Shuning Kong Hua Liu Yue Zhang Jiang Fan Wei Huang |
| author_facet | Shuning Kong Hua Liu Yue Zhang Jiang Fan Wei Huang |
| author_sort | Shuning Kong |
| collection | DOAJ |
| description | Summary: Currently, the primary imaging methods used in clinical diagnosis are X-ray, computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), PET-CT, etc. The sensitivity and accuracy of these imaging methods bring many difficulties in clinical diagnosis; at the same time, CT, X-ray, PET-CT, etc. can cause radiation to the human body; some invasive operations of the gold standard bring much pain to the patients. Some of these tests are costly and do not allow real-time in vivo imaging (IVI). For these reasons, a new field of nanoprobes is gradually being developed in the clinical direction. Nanoprobes are known for their noninvasive, highly sensitive, real-time IVI and can even be expanded to intracellular imaging. This paper introduces the mainstream nanomaterial probes and reviews them regarding imaging means, imaging principles, biosafety, and clinical application effects. |
| format | Article |
| id | doaj-art-48b997c8281c4cb68fb2fb3d0ac9045b |
| institution | OA Journals |
| issn | 2589-0042 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj-art-48b997c8281c4cb68fb2fb3d0ac9045b2025-08-20T02:01:33ZengElsevieriScience2589-00422025-01-0128111145910.1016/j.isci.2024.111459Clinical applications of nanoprobes of high-resolution in vivo imagingShuning Kong0Hua Liu1Yue Zhang2Jiang Fan3Wei Huang4Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Corresponding authorDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Corresponding authorSummary: Currently, the primary imaging methods used in clinical diagnosis are X-ray, computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), PET-CT, etc. The sensitivity and accuracy of these imaging methods bring many difficulties in clinical diagnosis; at the same time, CT, X-ray, PET-CT, etc. can cause radiation to the human body; some invasive operations of the gold standard bring much pain to the patients. Some of these tests are costly and do not allow real-time in vivo imaging (IVI). For these reasons, a new field of nanoprobes is gradually being developed in the clinical direction. Nanoprobes are known for their noninvasive, highly sensitive, real-time IVI and can even be expanded to intracellular imaging. This paper introduces the mainstream nanomaterial probes and reviews them regarding imaging means, imaging principles, biosafety, and clinical application effects.http://www.sciencedirect.com/science/article/pii/S2589004224026865Health sciencesNatural sciencesApplied sciences |
| spellingShingle | Shuning Kong Hua Liu Yue Zhang Jiang Fan Wei Huang Clinical applications of nanoprobes of high-resolution in vivo imaging iScience Health sciences Natural sciences Applied sciences |
| title | Clinical applications of nanoprobes of high-resolution in vivo imaging |
| title_full | Clinical applications of nanoprobes of high-resolution in vivo imaging |
| title_fullStr | Clinical applications of nanoprobes of high-resolution in vivo imaging |
| title_full_unstemmed | Clinical applications of nanoprobes of high-resolution in vivo imaging |
| title_short | Clinical applications of nanoprobes of high-resolution in vivo imaging |
| title_sort | clinical applications of nanoprobes of high resolution in vivo imaging |
| topic | Health sciences Natural sciences Applied sciences |
| url | http://www.sciencedirect.com/science/article/pii/S2589004224026865 |
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