Clinical applications of nanoprobes of high-resolution in vivo imaging

Summary: Currently, the primary imaging methods used in clinical diagnosis are X-ray, computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), PET-CT, etc. The sensitivity and accuracy of these imaging methods bring many difficulties in clinical diagnosis; at the same time, CT, X-ray,...

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Bibliographic Details
Main Authors: Shuning Kong, Hua Liu, Yue Zhang, Jiang Fan, Wei Huang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026865
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Summary:Summary: Currently, the primary imaging methods used in clinical diagnosis are X-ray, computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), PET-CT, etc. The sensitivity and accuracy of these imaging methods bring many difficulties in clinical diagnosis; at the same time, CT, X-ray, PET-CT, etc. can cause radiation to the human body; some invasive operations of the gold standard bring much pain to the patients. Some of these tests are costly and do not allow real-time in vivo imaging (IVI). For these reasons, a new field of nanoprobes is gradually being developed in the clinical direction. Nanoprobes are known for their noninvasive, highly sensitive, real-time IVI and can even be expanded to intracellular imaging. This paper introduces the mainstream nanomaterial probes and reviews them regarding imaging means, imaging principles, biosafety, and clinical application effects.
ISSN:2589-0042