Gap Expansion Between Cranial Bone and Polyether Ether Ketone Implant in Cranioplasty of Pediatric Patients after Decompressive Craniectomy at Follow-up
This study aimed to explore the experience and complications of cranioplasty (CP) with polyether ether ketone (PEEK) in pediatric and adolescent patients after decompressive craniectomy (DC). A total of 62 children (aged <18 years) with cranial bone defects due to DC underwent CP with a custom-ma...
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| Format: | Article |
| Language: | English |
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Mary Ann Liebert
2025-01-01
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| Series: | Neurotrauma Reports |
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| Online Access: | https://www.liebertpub.com/doi/10.1089/neur.2025.0007 |
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| author | Chuanwei Wang Chen Yang Runlu Zhang Yuan Zhang Yanzhao Wang Liping Ning Guoran Du Zhaoxi Sang Shilei Ni Xingang Li Jie Gong |
| author_facet | Chuanwei Wang Chen Yang Runlu Zhang Yuan Zhang Yanzhao Wang Liping Ning Guoran Du Zhaoxi Sang Shilei Ni Xingang Li Jie Gong |
| author_sort | Chuanwei Wang |
| collection | DOAJ |
| description | This study aimed to explore the experience and complications of cranioplasty (CP) with polyether ether ketone (PEEK) in pediatric and adolescent patients after decompressive craniectomy (DC). A total of 62 children (aged <18 years) with cranial bone defects due to DC underwent CP with a custom-made PEEK at our department between January 2018 and April 2023. The clinical characteristics, radiological features, surgical conditions, postoperative complications, and follow-up results of these patients were analyzed retrospectively. Kaplan–Meier survival analysis and Cox regression were used to analyze data. The age of the patients ranged from 2 to 17 years. The follow-up periods ranged from 12 to 70 months. Six patients experienced subcutaneous fluid accumulation (9.7%), five experienced epidural fluid accumulation (8.1%), and two experienced scalp inflammation (3.2%), which all were cured before discharge. Seven patients experienced bone gap expansion at the interface between the cranial bone and PEEK during follow-up (11.3%). Univariate analysis showed that DC-CP time interval (<3 months) and age were two influencing factors. Multivariate analysis revealed that age was the most important factor (p < 0.005, hazard ratio = 0.250, 95% confidence interval: 0.096–0.652). No reoperation was performed. Medical follow-ups were carried out further. For pediatric patients with cranial defects after DC who receive CP with a custom-made PEEK, two variables including younger age and too short DC-CP time interval may be unfavorable factors, to make patients experience bone gap expansion at the interface between the cranial bone and the PEEK. Additional data should be collected to validate our conclusions. |
| format | Article |
| id | doaj-art-48a8a6fcf59548c9bb710d7131c2f1ee |
| institution | Kabale University |
| issn | 2689-288X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Mary Ann Liebert |
| record_format | Article |
| series | Neurotrauma Reports |
| spelling | doaj-art-48a8a6fcf59548c9bb710d7131c2f1ee2025-08-20T03:41:03ZengMary Ann LiebertNeurotrauma Reports2689-288X2025-01-016166066810.1089/neur.2025.0007Gap Expansion Between Cranial Bone and Polyether Ether Ketone Implant in Cranioplasty of Pediatric Patients after Decompressive Craniectomy at Follow-upChuanwei Wang0Chen Yang1Runlu Zhang2Yuan Zhang3Yanzhao Wang4Liping Ning5Guoran Du6Zhaoxi Sang7Shilei Ni8Xingang Li9Jie Gong10Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.Clinical Epidemiology Unit, Qilu Hospital of Shandong University, Jinan, China.Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.Rehabilitation Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.Department of Neurosurgery, Qingyun People’s Hospital, Dezhou, China.Department of Neurosurgery, People’s Hospital of Chiping District, Liaocheng, China.Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan, China.This study aimed to explore the experience and complications of cranioplasty (CP) with polyether ether ketone (PEEK) in pediatric and adolescent patients after decompressive craniectomy (DC). A total of 62 children (aged <18 years) with cranial bone defects due to DC underwent CP with a custom-made PEEK at our department between January 2018 and April 2023. The clinical characteristics, radiological features, surgical conditions, postoperative complications, and follow-up results of these patients were analyzed retrospectively. Kaplan–Meier survival analysis and Cox regression were used to analyze data. The age of the patients ranged from 2 to 17 years. The follow-up periods ranged from 12 to 70 months. Six patients experienced subcutaneous fluid accumulation (9.7%), five experienced epidural fluid accumulation (8.1%), and two experienced scalp inflammation (3.2%), which all were cured before discharge. Seven patients experienced bone gap expansion at the interface between the cranial bone and PEEK during follow-up (11.3%). Univariate analysis showed that DC-CP time interval (<3 months) and age were two influencing factors. Multivariate analysis revealed that age was the most important factor (p < 0.005, hazard ratio = 0.250, 95% confidence interval: 0.096–0.652). No reoperation was performed. Medical follow-ups were carried out further. For pediatric patients with cranial defects after DC who receive CP with a custom-made PEEK, two variables including younger age and too short DC-CP time interval may be unfavorable factors, to make patients experience bone gap expansion at the interface between the cranial bone and the PEEK. Additional data should be collected to validate our conclusions.https://www.liebertpub.com/doi/10.1089/neur.2025.0007adolescencechildrencranioplastypediatricspolyether ether ketone |
| spellingShingle | Chuanwei Wang Chen Yang Runlu Zhang Yuan Zhang Yanzhao Wang Liping Ning Guoran Du Zhaoxi Sang Shilei Ni Xingang Li Jie Gong Gap Expansion Between Cranial Bone and Polyether Ether Ketone Implant in Cranioplasty of Pediatric Patients after Decompressive Craniectomy at Follow-up Neurotrauma Reports adolescence children cranioplasty pediatrics polyether ether ketone |
| title | Gap Expansion Between Cranial Bone and Polyether Ether Ketone Implant in Cranioplasty of Pediatric Patients after Decompressive Craniectomy at Follow-up |
| title_full | Gap Expansion Between Cranial Bone and Polyether Ether Ketone Implant in Cranioplasty of Pediatric Patients after Decompressive Craniectomy at Follow-up |
| title_fullStr | Gap Expansion Between Cranial Bone and Polyether Ether Ketone Implant in Cranioplasty of Pediatric Patients after Decompressive Craniectomy at Follow-up |
| title_full_unstemmed | Gap Expansion Between Cranial Bone and Polyether Ether Ketone Implant in Cranioplasty of Pediatric Patients after Decompressive Craniectomy at Follow-up |
| title_short | Gap Expansion Between Cranial Bone and Polyether Ether Ketone Implant in Cranioplasty of Pediatric Patients after Decompressive Craniectomy at Follow-up |
| title_sort | gap expansion between cranial bone and polyether ether ketone implant in cranioplasty of pediatric patients after decompressive craniectomy at follow up |
| topic | adolescence children cranioplasty pediatrics polyether ether ketone |
| url | https://www.liebertpub.com/doi/10.1089/neur.2025.0007 |
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