Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy
Polymyositis-dermatomyositis is extremely rare during pregnancy, and immunosuppressive therapy should be administered after carefully considering the effects on both the mother and fetus. Several reports have associated the disease activity with fetal prognosis, higher rates of eclampsia, preterm bi...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2019/4914631 |
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| author | Saito Mayu Sakiko Isojima Yoko Miura Shinichiro Nishimi Mika Hatano Takahiro Tokunaga Ryo Takahashi Keiko Koide Yusuke Miwa |
| author_facet | Saito Mayu Sakiko Isojima Yoko Miura Shinichiro Nishimi Mika Hatano Takahiro Tokunaga Ryo Takahashi Keiko Koide Yusuke Miwa |
| author_sort | Saito Mayu |
| collection | DOAJ |
| description | Polymyositis-dermatomyositis is extremely rare during pregnancy, and immunosuppressive therapy should be administered after carefully considering the effects on both the mother and fetus. Several reports have associated the disease activity with fetal prognosis, higher rates of eclampsia, preterm births, and fetal deaths. We report our experience with a patient who was diagnosed with polymyositis-dermatomyositis complicated by interstitial lung disease during pregnancy and was treated with a combination-immunosuppressant regimen. To the best of our knowledge, this is the first case wherein cyclosporine was used concomitantly with a steroid for the treatment of polymyositis diagnosed during pregnancy, with successful outcome of childbirth without any complications. |
| format | Article |
| id | doaj-art-48999db9c17f4c9a975a40fff7feb375 |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-48999db9c17f4c9a975a40fff7feb3752025-02-03T05:54:15ZengWileyCase Reports in Rheumatology2090-68892090-68972019-01-01201910.1155/2019/49146314914631Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid TherapySaito Mayu0Sakiko Isojima1Yoko Miura2Shinichiro Nishimi3Mika Hatano4Takahiro Tokunaga5Ryo Takahashi6Keiko Koide7Yusuke Miwa8Department of Rheumatology, Showa University School of Medicine, Tokyo, JapanDepartment of Rheumatology, Showa University School of Medicine, Tokyo, JapanDepartment of Rheumatology, Showa University School of Medicine, Tokyo, JapanDepartment of Rheumatology, Showa University School of Medicine, Tokyo, JapanDepartment of Rheumatology, Showa University School of Medicine, Tokyo, JapanDepartment of Rheumatology, Showa University School of Medicine, Tokyo, JapanDepartment of Rheumatology, Showa University School of Medicine, Tokyo, JapanDivision of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, JapanDepartment of Rheumatology, Showa University School of Medicine, Tokyo, JapanPolymyositis-dermatomyositis is extremely rare during pregnancy, and immunosuppressive therapy should be administered after carefully considering the effects on both the mother and fetus. Several reports have associated the disease activity with fetal prognosis, higher rates of eclampsia, preterm births, and fetal deaths. We report our experience with a patient who was diagnosed with polymyositis-dermatomyositis complicated by interstitial lung disease during pregnancy and was treated with a combination-immunosuppressant regimen. To the best of our knowledge, this is the first case wherein cyclosporine was used concomitantly with a steroid for the treatment of polymyositis diagnosed during pregnancy, with successful outcome of childbirth without any complications.http://dx.doi.org/10.1155/2019/4914631 |
| spellingShingle | Saito Mayu Sakiko Isojima Yoko Miura Shinichiro Nishimi Mika Hatano Takahiro Tokunaga Ryo Takahashi Keiko Koide Yusuke Miwa Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy Case Reports in Rheumatology |
| title | Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy |
| title_full | Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy |
| title_fullStr | Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy |
| title_full_unstemmed | Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy |
| title_short | Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy |
| title_sort | polymyositis dermatomyositis and interstitial lung disease in pregnant woman successfully treated with cyclosporine and tapered steroid therapy |
| url | http://dx.doi.org/10.1155/2019/4914631 |
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