Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy
Immunotherapy is a promising strategy for nasopharyngeal carcinoma (NPC), a common and aggressive malignancy with poor prognosis. However, the literature lacks a comprehensive and objective overview of the current research status and trends of immunotherapy-related fields in NPC. We performed a bibl...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/21645515.2024.2360341 |
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| author | Gang Wang Xiaosu Zou Jingjin Weng Guiping Lan Min Li Jiazhang Wei Wenqian Nong Qicong Chen Weiwei Miao Honglin Luo Shenhong Qu |
| author_facet | Gang Wang Xiaosu Zou Jingjin Weng Guiping Lan Min Li Jiazhang Wei Wenqian Nong Qicong Chen Weiwei Miao Honglin Luo Shenhong Qu |
| author_sort | Gang Wang |
| collection | DOAJ |
| description | Immunotherapy is a promising strategy for nasopharyngeal carcinoma (NPC), a common and aggressive malignancy with poor prognosis. However, the literature lacks a comprehensive and objective overview of the current research status and trends of immunotherapy-related fields in NPC. We performed a bibliometric analysis of 513 original articles and reviews in English on immunotherapy for NPC from the Web of Science Core Collection database, using CiteSpace and Bibliometrix software tools. We visualized the development trend of publications, the distribution of countries/regions, the co-occurrence of keywords, the collaboration and citation of authors, the citation of journals, the evolution of topics, and the thematic map. We found that the publication volume increased sharply after 2017, with China as the main contributor and leader, the US as an important partner, and the Netherlands as a potential innovator. The research focused on immune checkpoint inhibitors and cell therapy, which were also the hotspots of clinical trials. Tumor microenvironment, immune infiltration, multicenter studies, and novel immunotherapy were the frontier topics and the key challenges for future research. CD137l-DC, lymphoma, and chimeric antigen receptor were emerging topics with good prospects. Our study provides a valuable insight into the research status and trends of immunotherapy for NPC, which may guide future research directions and clinical applications. |
| format | Article |
| id | doaj-art-48972a49fb4e47608495a2170e88a494 |
| institution | OA Journals |
| issn | 2164-5515 2164-554X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj-art-48972a49fb4e47608495a2170e88a4942025-08-20T02:01:20ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2024-12-0120110.1080/21645515.2024.2360341Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapyGang Wang0Xiaosu Zou1Jingjin Weng2Guiping Lan3Min Li4Jiazhang Wei5Wenqian Nong6Qicong Chen7Weiwei Miao8Honglin Luo9Shenhong Qu10Institute of Oncology, Guangxi Academy of Medical Sciences, Nanning, Guangxi, ChinaInstitute of Oncology, Guangxi Academy of Medical Sciences, Nanning, Guangxi, ChinaDepartment of Otolaryngology & Head and Neck, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, ChinaDepartment of Otolaryngology & Head and Neck, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, ChinaDepartment of Otolaryngology & Head and Neck, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, ChinaDepartment of Otolaryngology & Head and Neck, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, ChinaInstitute of Oncology, Guangxi Academy of Medical Sciences, Nanning, Guangxi, ChinaInstitute of Oncology, Guangxi Academy of Medical Sciences, Nanning, Guangxi, ChinaInstitute of Oncology, Guangxi Academy of Medical Sciences, Nanning, Guangxi, ChinaInstitute of Oncology, Guangxi Academy of Medical Sciences, Nanning, Guangxi, ChinaInstitute of Oncology, Guangxi Academy of Medical Sciences, Nanning, Guangxi, ChinaImmunotherapy is a promising strategy for nasopharyngeal carcinoma (NPC), a common and aggressive malignancy with poor prognosis. However, the literature lacks a comprehensive and objective overview of the current research status and trends of immunotherapy-related fields in NPC. We performed a bibliometric analysis of 513 original articles and reviews in English on immunotherapy for NPC from the Web of Science Core Collection database, using CiteSpace and Bibliometrix software tools. We visualized the development trend of publications, the distribution of countries/regions, the co-occurrence of keywords, the collaboration and citation of authors, the citation of journals, the evolution of topics, and the thematic map. We found that the publication volume increased sharply after 2017, with China as the main contributor and leader, the US as an important partner, and the Netherlands as a potential innovator. The research focused on immune checkpoint inhibitors and cell therapy, which were also the hotspots of clinical trials. Tumor microenvironment, immune infiltration, multicenter studies, and novel immunotherapy were the frontier topics and the key challenges for future research. CD137l-DC, lymphoma, and chimeric antigen receptor were emerging topics with good prospects. Our study provides a valuable insight into the research status and trends of immunotherapy for NPC, which may guide future research directions and clinical applications.https://www.tandfonline.com/doi/10.1080/21645515.2024.2360341Nasopharyngeal carcinomaimmunotherapybibliometric analysisimmune checkpoint inhibitorstumor microenvironment |
| spellingShingle | Gang Wang Xiaosu Zou Jingjin Weng Guiping Lan Min Li Jiazhang Wei Wenqian Nong Qicong Chen Weiwei Miao Honglin Luo Shenhong Qu Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy Human Vaccines & Immunotherapeutics Nasopharyngeal carcinoma immunotherapy bibliometric analysis immune checkpoint inhibitors tumor microenvironment |
| title | Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy |
| title_full | Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy |
| title_fullStr | Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy |
| title_full_unstemmed | Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy |
| title_short | Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy |
| title_sort | bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy |
| topic | Nasopharyngeal carcinoma immunotherapy bibliometric analysis immune checkpoint inhibitors tumor microenvironment |
| url | https://www.tandfonline.com/doi/10.1080/21645515.2024.2360341 |
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