Circumferential Endoscopic Submucosal Dissection for Barrett's Esophagus with Multifocal High-Grade Dysplasia
A 54-year-old male presented with longstanding history of heartburn and regurgitation. Upper gastrointestinal endoscopy and biopsy performed at the previous center were suggestive of Barrett's esophagus with high-grade dysplasia (HGD). In view of dysplasia with underlying Barrett's esophag...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2024-12-01
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| Series: | Journal of Digestive Endoscopy |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1791953 |
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| Summary: | A 54-year-old male presented with longstanding history of heartburn and regurgitation. Upper gastrointestinal endoscopy and biopsy performed at the previous center were suggestive of Barrett's esophagus with high-grade dysplasia (HGD). In view of dysplasia with underlying Barrett's esophagus, endoscopic submucosal dissection (ESD) was planned. Multifocal high-grade dysplasia with underlying Barrett's esophagus needs treatment to prevent invasive cancer. Surgery has been the conventional treatment but is associated with morbid complications and mortality. ESD has emerged as a treatment for HGD and superficial adenocarcinoma in Barrett's segment, but circumferential ESD is associated with risk of stricture formation. The present case highlights the role of image-enhanced endoscopy in identifying dysplasia in Barrett's esophagus and minimally invasive endoscopic techniques as an alternative to conventional surgical techniques and prophylactic measures needed to prevent post-ESD complications. |
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| ISSN: | 0976-5042 0976-5050 |