Disseminated Cunninghamella bertholletiae Infection During Induction Chemotherapy in a Girl with High-Risk Acute Lymphoblastic Leukemia
Invasive fungal infections in children with acute lymphoblastic leukemia have been a major cause of mortality. Recent reports have described increasing incidence of invasive non-Aspergillus mold infections in patients with hematological malignancies. It is always challenging to treat invasive fungal...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-12-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957214001399 |
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| author | Yung-Yueh Su Tsung-Yen Chang Chao-Jan Wang Tang-Her Jaing Chuen Hsueh Cheng-Hsun Chiu Yhu-Chering Huang Shih-Hsiang Chen |
| author_facet | Yung-Yueh Su Tsung-Yen Chang Chao-Jan Wang Tang-Her Jaing Chuen Hsueh Cheng-Hsun Chiu Yhu-Chering Huang Shih-Hsiang Chen |
| author_sort | Yung-Yueh Su |
| collection | DOAJ |
| description | Invasive fungal infections in children with acute lymphoblastic leukemia have been a major cause of mortality. Recent reports have described increasing incidence of invasive non-Aspergillus mold infections in patients with hematological malignancies. It is always challenging to treat invasive fungal infection and underlying hematological malignancies successfully. Here we report a girl with high-risk acute lymphoblastic leukemia who developed disseminated Cunninghamella bertholletiae infection during induction chemotherapy. This case illustrates the difficulties of diagnosis and treatment of invasive C. bertholletiae infection. It also highlights the necessity for physicians to keep high suspicion and awareness for this infrequent fungal infection. |
| format | Article |
| id | doaj-art-487a8d28da4d40ea82da6fe08944f0c6 |
| institution | DOAJ |
| issn | 1875-9572 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-487a8d28da4d40ea82da6fe08944f0c62025-08-20T03:09:58ZengElsevierPediatrics and Neonatology1875-95722016-12-0157653153410.1016/j.pedneo.2014.04.010Disseminated Cunninghamella bertholletiae Infection During Induction Chemotherapy in a Girl with High-Risk Acute Lymphoblastic LeukemiaYung-Yueh Su0Tsung-Yen Chang1Chao-Jan Wang2Tang-Her Jaing3Chuen Hsueh4Cheng-Hsun Chiu5Yhu-Chering Huang6Shih-Hsiang Chen7Department of Nuclear Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Diagnostic Radiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pathology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanInvasive fungal infections in children with acute lymphoblastic leukemia have been a major cause of mortality. Recent reports have described increasing incidence of invasive non-Aspergillus mold infections in patients with hematological malignancies. It is always challenging to treat invasive fungal infection and underlying hematological malignancies successfully. Here we report a girl with high-risk acute lymphoblastic leukemia who developed disseminated Cunninghamella bertholletiae infection during induction chemotherapy. This case illustrates the difficulties of diagnosis and treatment of invasive C. bertholletiae infection. It also highlights the necessity for physicians to keep high suspicion and awareness for this infrequent fungal infection.http://www.sciencedirect.com/science/article/pii/S1875957214001399acute lymphoblastic leukemiachildrenCunninghamella bertholletiaeinvasive fungal infectionmucormycosis |
| spellingShingle | Yung-Yueh Su Tsung-Yen Chang Chao-Jan Wang Tang-Her Jaing Chuen Hsueh Cheng-Hsun Chiu Yhu-Chering Huang Shih-Hsiang Chen Disseminated Cunninghamella bertholletiae Infection During Induction Chemotherapy in a Girl with High-Risk Acute Lymphoblastic Leukemia Pediatrics and Neonatology acute lymphoblastic leukemia children Cunninghamella bertholletiae invasive fungal infection mucormycosis |
| title | Disseminated Cunninghamella bertholletiae Infection During Induction Chemotherapy in a Girl with High-Risk Acute Lymphoblastic Leukemia |
| title_full | Disseminated Cunninghamella bertholletiae Infection During Induction Chemotherapy in a Girl with High-Risk Acute Lymphoblastic Leukemia |
| title_fullStr | Disseminated Cunninghamella bertholletiae Infection During Induction Chemotherapy in a Girl with High-Risk Acute Lymphoblastic Leukemia |
| title_full_unstemmed | Disseminated Cunninghamella bertholletiae Infection During Induction Chemotherapy in a Girl with High-Risk Acute Lymphoblastic Leukemia |
| title_short | Disseminated Cunninghamella bertholletiae Infection During Induction Chemotherapy in a Girl with High-Risk Acute Lymphoblastic Leukemia |
| title_sort | disseminated cunninghamella bertholletiae infection during induction chemotherapy in a girl with high risk acute lymphoblastic leukemia |
| topic | acute lymphoblastic leukemia children Cunninghamella bertholletiae invasive fungal infection mucormycosis |
| url | http://www.sciencedirect.com/science/article/pii/S1875957214001399 |
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