Proteomic Comparison of Acute Myeloid Leukemia Cells and Normal CD34<sup>+</sup> Bone Marrow Cells: Studies of Leukemia Cell Differentiation and Regulation of Iron Metabolism/Ferroptosis

Proteomic Comparison of Acute Myeloid Leukemia Cells and Normal CD34<sup>+</sup> Bone Marrow Cells: Studies of Leukemia Cell Differentiation and Regulation of Iron Metabolism/Ferroptosis

Acute myeloid leukemia (AML) is an aggressive bone marrow malignancy that can be cured only by intensive chemotherapy possibly combined with allogeneic stem cell transplantation. We compared the pretreatment proteomic profiles of AML cells derived from 50 patients at the time of first diagnosis with...

Full description

Saved in:
Bibliographic Details
Main Authors: Frode Selheim, Elise Aasebø, Håkon Reikvam, Øystein Bruserud, Maria Hernandez-Valladares
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Proteomes
Subjects:
acute myeloid leukemia
normal CD34<sup>+</sup> bone marrow cells
hematopoiesis
differentiation
integrin
Toll-like receptor
Online Access:https://www.mdpi.com/2227-7382/13/1/11
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items