Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysis
BackgroundHearing loss ranks as the third most prevalent disability globally, significantly impacting individuals and society, and imposing a substantial healthcare burden. The World Health Organization reports that over 1.5 billion people worldwide experience hearing loss, with one-third of these c...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2025.1528771/full |
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| author | Wang Lu Wang Lu Rui Tang Xiong Jiahui Zhang Shipeng Guo Tao Wang Hanyua Xiong Feng Xie Hui Xie Hui |
| author_facet | Wang Lu Wang Lu Rui Tang Xiong Jiahui Zhang Shipeng Guo Tao Wang Hanyua Xiong Feng Xie Hui Xie Hui |
| author_sort | Wang Lu |
| collection | DOAJ |
| description | BackgroundHearing loss ranks as the third most prevalent disability globally, significantly impacting individuals and society, and imposing a substantial healthcare burden. The World Health Organization reports that over 1.5 billion people worldwide experience hearing loss, with one-third of these cases attributed to preventable factors. Recently, the influence of diet and nutrition on auditory health has garnered increasing attention.ObjectiveThis study systematically reviews and meta-analyzes the protective effects of dietary nutrients on hearing, examining specific nutrients' impact on hearing loss and their potential biological mechanisms.MethodsA comprehensive search of PubMed, Embase, Web of Science, and the Cochrane Library was conducted for relevant studies up to August 2024. Following PRISMA guidelines, the systematic review was registered in PROSPERO. Included were observational studies assessing the relationship between dietary intake and hearing loss.ResultsThirty-three studies met inclusion criteria: 21 cross-sectional, 10 cohort, and 2 case-control studies. Meta-analysis revealed significant inverse associations between the intake of vitamin B2, β-carotene, carotenoids, β-cryptoxanthin, fat, protein, fiber, and fish, and the risk of hearing loss.ConclusionCertain dietary nutrients may protect hearing health. Increasing intake of antioxidants, fiber, protein, and fish rich in unsaturated fatty acids may help preserve auditory function.Keywords: Hearing loss, dietary nutrients, systematic review, meta-analysis, antioxidants.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/view/CRD42024572118, identifier: CRD42024572118. |
| format | Article |
| id | doaj-art-48731755501440f18e53f2bf76523d44 |
| institution | OA Journals |
| issn | 2296-861X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj-art-48731755501440f18e53f2bf76523d442025-08-20T02:28:33ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-05-011210.3389/fnut.2025.15287711528771Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysisWang Lu0Wang Lu1Rui Tang2Xiong Jiahui3Zhang Shipeng4Guo Tao5Wang Hanyua6Xiong Feng7Xie Hui8Xie Hui9Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, ChinaDepartment of Psychiatry and Psychotherapy, TUM School of Medicine and Health, Klinikum Rechts der Isar, Technical University of Munich, Munich, GermanyClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Orthopedics, Jiang'an County Traditional Chinese Medicine Hospital, Yibin, Sichuan, ChinaClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaOtolaryngology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaBackgroundHearing loss ranks as the third most prevalent disability globally, significantly impacting individuals and society, and imposing a substantial healthcare burden. The World Health Organization reports that over 1.5 billion people worldwide experience hearing loss, with one-third of these cases attributed to preventable factors. Recently, the influence of diet and nutrition on auditory health has garnered increasing attention.ObjectiveThis study systematically reviews and meta-analyzes the protective effects of dietary nutrients on hearing, examining specific nutrients' impact on hearing loss and their potential biological mechanisms.MethodsA comprehensive search of PubMed, Embase, Web of Science, and the Cochrane Library was conducted for relevant studies up to August 2024. Following PRISMA guidelines, the systematic review was registered in PROSPERO. Included were observational studies assessing the relationship between dietary intake and hearing loss.ResultsThirty-three studies met inclusion criteria: 21 cross-sectional, 10 cohort, and 2 case-control studies. Meta-analysis revealed significant inverse associations between the intake of vitamin B2, β-carotene, carotenoids, β-cryptoxanthin, fat, protein, fiber, and fish, and the risk of hearing loss.ConclusionCertain dietary nutrients may protect hearing health. Increasing intake of antioxidants, fiber, protein, and fish rich in unsaturated fatty acids may help preserve auditory function.Keywords: Hearing loss, dietary nutrients, systematic review, meta-analysis, antioxidants.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/view/CRD42024572118, identifier: CRD42024572118.https://www.frontiersin.org/articles/10.3389/fnut.2025.1528771/fullhearing lossdietary nutrientssystematic reviewmeta-analysisantioxidants |
| spellingShingle | Wang Lu Wang Lu Rui Tang Xiong Jiahui Zhang Shipeng Guo Tao Wang Hanyua Xiong Feng Xie Hui Xie Hui Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysis Frontiers in Nutrition hearing loss dietary nutrients systematic review meta-analysis antioxidants |
| title | Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysis |
| title_full | Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysis |
| title_fullStr | Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysis |
| title_full_unstemmed | Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysis |
| title_short | Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysis |
| title_sort | protective effects of dietary nutrients on hearing loss a systematic review and meta analysis |
| topic | hearing loss dietary nutrients systematic review meta-analysis antioxidants |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2025.1528771/full |
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