Concurrent spinal schwannoma and meningioma without neurofibromatosis: case presentation and review of literature

Abstract Background Concurrent multiple tumors developing in the spinal cord are rare, except for in genetic disorders, such as neurofibromatosis and von Hippel–Lindau disease. The presence of multiple histologically different spinal tumors in the absence of NF-2 is extremely rare. Schwannoma and me...

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Main Authors: Hossam Elnoamany, Mohammud Salim
Format: Article
Language:English
Published: SpringerOpen 2024-11-01
Series:Egyptian Journal of Neurosurgery
Subjects:
Online Access:https://doi.org/10.1186/s41984-024-00334-0
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author Hossam Elnoamany
Mohammud Salim
author_facet Hossam Elnoamany
Mohammud Salim
author_sort Hossam Elnoamany
collection DOAJ
description Abstract Background Concurrent multiple tumors developing in the spinal cord are rare, except for in genetic disorders, such as neurofibromatosis and von Hippel–Lindau disease. The presence of multiple histologically different spinal tumors in the absence of NF-2 is extremely rare. Schwannoma and meningioma can be explained partly by their common origin from the same mesenchymal cell, there is currently no explanation for the simultaneous existence of different spinal tumors other than simple coincidence. Case presentation After review of literature, there are thirteen such cases reported in the literature in addition to the present case. The current patient presents with lower limb weakness, and the patient radiology revealed intradural mass opposite the fourth lumbar vertebra with contrast enhancement and intradural extramedullary mass opposite the tenth dorsal vertebra with contrast enhancement in MRI spine. The coexistence of these tumors may be coincidental or might be due to a common histological origin of the Schwann cells and the meningocytes. Conclusion Schwannoma and meningioma have different radiological characteristics and require different managing procedures such as dural base coagulation in meningiomas and rootlet sacrifice in schwannomas.
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spelling doaj-art-486cc3ba5ae24c22813b3812dd5a8cb42025-08-20T02:32:52ZengSpringerOpenEgyptian Journal of Neurosurgery2520-82252024-11-013911510.1186/s41984-024-00334-0Concurrent spinal schwannoma and meningioma without neurofibromatosis: case presentation and review of literatureHossam Elnoamany0Mohammud Salim1Department of Neurosurgery, Menoufia University Hospital, Faculty of Medicine, Menoufia UniversityDepartment of Neurosurgery, Menoufia University Hospital, Faculty of Medicine, Menoufia UniversityAbstract Background Concurrent multiple tumors developing in the spinal cord are rare, except for in genetic disorders, such as neurofibromatosis and von Hippel–Lindau disease. The presence of multiple histologically different spinal tumors in the absence of NF-2 is extremely rare. Schwannoma and meningioma can be explained partly by their common origin from the same mesenchymal cell, there is currently no explanation for the simultaneous existence of different spinal tumors other than simple coincidence. Case presentation After review of literature, there are thirteen such cases reported in the literature in addition to the present case. The current patient presents with lower limb weakness, and the patient radiology revealed intradural mass opposite the fourth lumbar vertebra with contrast enhancement and intradural extramedullary mass opposite the tenth dorsal vertebra with contrast enhancement in MRI spine. The coexistence of these tumors may be coincidental or might be due to a common histological origin of the Schwann cells and the meningocytes. Conclusion Schwannoma and meningioma have different radiological characteristics and require different managing procedures such as dural base coagulation in meningiomas and rootlet sacrifice in schwannomas.https://doi.org/10.1186/s41984-024-00334-0Case reportConcurrent tumorIntraduralMeningiomaSchwannoma
spellingShingle Hossam Elnoamany
Mohammud Salim
Concurrent spinal schwannoma and meningioma without neurofibromatosis: case presentation and review of literature
Egyptian Journal of Neurosurgery
Case report
Concurrent tumor
Intradural
Meningioma
Schwannoma
title Concurrent spinal schwannoma and meningioma without neurofibromatosis: case presentation and review of literature
title_full Concurrent spinal schwannoma and meningioma without neurofibromatosis: case presentation and review of literature
title_fullStr Concurrent spinal schwannoma and meningioma without neurofibromatosis: case presentation and review of literature
title_full_unstemmed Concurrent spinal schwannoma and meningioma without neurofibromatosis: case presentation and review of literature
title_short Concurrent spinal schwannoma and meningioma without neurofibromatosis: case presentation and review of literature
title_sort concurrent spinal schwannoma and meningioma without neurofibromatosis case presentation and review of literature
topic Case report
Concurrent tumor
Intradural
Meningioma
Schwannoma
url https://doi.org/10.1186/s41984-024-00334-0
work_keys_str_mv AT hossamelnoamany concurrentspinalschwannomaandmeningiomawithoutneurofibromatosiscasepresentationandreviewofliterature
AT mohammudsalim concurrentspinalschwannomaandmeningiomawithoutneurofibromatosiscasepresentationandreviewofliterature