Transcriptomic Profiling of Hypoxia-Adaptive Responses in Tibetan Goat Fibroblasts

Transcriptomic Profiling of Hypoxia-Adaptive Responses in Tibetan Goat Fibroblasts

The Tibetan goat (<i>Capra hircus</i>) exhibits remarkable adaptations to high-altitude hypoxia, yet the molecular mechanisms remain unclear. This study integrates RNA-seq, WGCNA, and machine learning to explore gene-environment interactions (G × E) in hypoxia adaptation. Fibroblasts fro...

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Bibliographic Details
Main Authors: Lin Tang, Li Zhu, Zhuzha Basang, Yunong Zhao, Shanshan Li, Xiaoyan Kong, Xiao Gou
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Animals
Subjects:
gene–environment interactions
DEGs
machine learning
WGCNA
HIF-1 signaling pathway
Online Access:https://www.mdpi.com/2076-2615/15/10/1407
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