Advances in MoS<sub>2</sub>-Based Biosensors: From Material Fabrication and Characterization to Biomedical, Environmental, and Industrial Applications
The growing demand for low-cost biosensors has stimulated the study of new technologies and materials like molybdenum disulfide (MoS<sub>2</sub>). Due to its electroconductive nature and high surface-to-volume ratio, it allows for the ultra-sensitive detection of biomarkers. The crystal...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
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| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/15/6/371 |
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| Summary: | The growing demand for low-cost biosensors has stimulated the study of new technologies and materials like molybdenum disulfide (MoS<sub>2</sub>). Due to its electroconductive nature and high surface-to-volume ratio, it allows for the ultra-sensitive detection of biomarkers. The crystal structure of MoS<sub>2</sub> provides it with a unique micrometer thickness, making it appropriate for biosensing in healthcare, environmental monitoring, and food safety. As compared to traditional materials, MoS<sub>2</sub> can work without labels (through field-effect transduction or plasmonic shifts) while maintaining biocompatibility and low-cost fabrication, which fill significant voids in the early diagnosis of diseases. This paper provides an overview of the recent advancements in MoS<sub>2</sub>-based biosensors, which are primarily focused on the field-effect transistors and surface plasmon resonance techniques and fabrication methods for MoS<sub>2</sub>-based biosensors like mechanical exfoliation, liquid-phase exfoliation, physical vapor deposition, chemical vapor deposition, and chemical exfoliation, applications in various industries, and their characterization techniques to evaluate the quality and functionality of MoS<sub>2</sub> nanosheets in biosensors. While certain challenges remain like improving conductivity and scalability, MoS<sub>2</sub>-based biosensors serve as a powerful tool for the precise and reliable detection of biomarkers in environmental, food, and healthcare industries. |
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| ISSN: | 2079-6374 |