−254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children

−254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children

This study is aimed at exploring the mechanism by which the −254C>G single nucleotide polymorphism (SNP) on the transient receptor potential cation channel 6 (TRPC6) gene promoter could increase its activation in steroid-resistant nephrotic syndrome children of China. Plasmids containing the TRPC...

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Bibliographic Details
Main Authors: Xinyu Kuang, Qian Zhou, Zhuying Li, Yujie Hu, Yulin Kang, Wenyan Huang
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2019/2197837
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