Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread
Gastric cancer often carries a poor prognosis, with an estimated 740,000 deaths from the malignancy occurring yearly worldwide (Dicken et al., 2005). The mortality of disease is largely dependent on the extent of tumor spread, as gastric cancer has a predilection to metastasize to other visceral sec...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/651232 |
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| author | Mitanshu Shah Apsara Prasad Dhyan Rajan Christopher B. Tan Mansi Shah Pooja Raghavan Paul Mustacchia |
| author_facet | Mitanshu Shah Apsara Prasad Dhyan Rajan Christopher B. Tan Mansi Shah Pooja Raghavan Paul Mustacchia |
| author_sort | Mitanshu Shah |
| collection | DOAJ |
| description | Gastric cancer often carries a poor prognosis, with an estimated 740,000 deaths from the malignancy occurring yearly worldwide (Dicken et al., 2005). The mortality of disease is largely dependent on the extent of tumor spread, as gastric cancer has a predilection to metastasize to other visceral secondaries via hematogenous and lymphatic dissemination. Direct invasion of a gastric adenocarcinoma to adjacent organs secondary to gastric wall perforation does occur; however, it is often present in the setting of advanced disease. Rarely does direct tumor invasion to adjacent organs from a gastric adenocarcinoma present as the initial manifestation of extranodal tumor spread. We present a case of a 40-year-old male with direct tumor extension to the liver as an initial presentation of extranodal tumor spread from a gastric adenocarcinoma. Clinicians should be aware of such an occurrence, as treatment modalities in direct liver extension from a gastric adenocarcinoma vary and may be directed towards palliation rather than curative intent. |
| format | Article |
| id | doaj-art-483ab0adeed342a9974a62d796fc2f8f |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-483ab0adeed342a9974a62d796fc2f8f2025-08-20T02:38:01ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/651232651232Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor SpreadMitanshu Shah0Apsara Prasad1Dhyan Rajan2Christopher B. Tan3Mansi Shah4Pooja Raghavan5Paul Mustacchia6Department of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Gastroenterology, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Medicine, New York College of Osteopathic Medicine, Old Westbury, NY 11568, USADepartment of Internal Medicine, Mount Carmel Health, Columbus, OH 43222, USADepartment of Gastroenterology, Nassau University Medical Center, East Meadow, NY 11554, USAGastric cancer often carries a poor prognosis, with an estimated 740,000 deaths from the malignancy occurring yearly worldwide (Dicken et al., 2005). The mortality of disease is largely dependent on the extent of tumor spread, as gastric cancer has a predilection to metastasize to other visceral secondaries via hematogenous and lymphatic dissemination. Direct invasion of a gastric adenocarcinoma to adjacent organs secondary to gastric wall perforation does occur; however, it is often present in the setting of advanced disease. Rarely does direct tumor invasion to adjacent organs from a gastric adenocarcinoma present as the initial manifestation of extranodal tumor spread. We present a case of a 40-year-old male with direct tumor extension to the liver as an initial presentation of extranodal tumor spread from a gastric adenocarcinoma. Clinicians should be aware of such an occurrence, as treatment modalities in direct liver extension from a gastric adenocarcinoma vary and may be directed towards palliation rather than curative intent.http://dx.doi.org/10.1155/2012/651232 |
| spellingShingle | Mitanshu Shah Apsara Prasad Dhyan Rajan Christopher B. Tan Mansi Shah Pooja Raghavan Paul Mustacchia Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread Case Reports in Medicine |
| title | Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread |
| title_full | Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread |
| title_fullStr | Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread |
| title_full_unstemmed | Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread |
| title_short | Direct Liver Invasion from a Gastric Adenocarcinoma as an Initial Presentation of Extranodal Tumor Spread |
| title_sort | direct liver invasion from a gastric adenocarcinoma as an initial presentation of extranodal tumor spread |
| url | http://dx.doi.org/10.1155/2012/651232 |
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