Molecular aspects of the T-helpers type 17 functioning

The article presents up-to-date data on the functioning of the T-helper type 17 (Th17). History of the Th17 discovery, transcription factors, mechanisms, mediating stimulation and inhibition of the Th17 differentiation, are described. Cytokines, which are produced by this lymphoid subset, and signal...

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Main Authors: I. V. Kologrivova, Ye. N. Kologrivova, T. Ye. Suslova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2011-08-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/1435
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author I. V. Kologrivova
Ye. N. Kologrivova
T. Ye. Suslova
author_facet I. V. Kologrivova
Ye. N. Kologrivova
T. Ye. Suslova
author_sort I. V. Kologrivova
collection DOAJ
description The article presents up-to-date data on the functioning of the T-helper type 17 (Th17). History of the Th17 discovery, transcription factors, mechanisms, mediating stimulation and inhibition of the Th17 differentiation, are described. Cytokines, which are produced by this lymphoid subset, and signaling pathways, through which its effects are realized, are listed. A brief description is given of the main physiological processes and diseases, in which participation of the Th17 was described.
format Article
id doaj-art-483a4648abec4bb6bcca2fedd17357eb
institution Kabale University
issn 1682-0363
1819-3684
language English
publishDate 2011-08-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-483a4648abec4bb6bcca2fedd17357eb2025-08-20T04:00:19ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-08-01104939810.20538/1682-0363-2011-4-93-98945Molecular aspects of the T-helpers type 17 functioningI. V. Kologrivova0Ye. N. Kologrivova1T. Ye. Suslova2НИИ кардиологии СО РАМНСибирский государственный медицинский университетНИИ кардиологии СО РАМНThe article presents up-to-date data on the functioning of the T-helper type 17 (Th17). History of the Th17 discovery, transcription factors, mechanisms, mediating stimulation and inhibition of the Th17 differentiation, are described. Cytokines, which are produced by this lymphoid subset, and signaling pathways, through which its effects are realized, are listed. A brief description is given of the main physiological processes and diseases, in which participation of the Th17 was described.https://bulletin.ssmu.ru/jour/article/view/1435t helper type 17cytokinesimmune regulation
spellingShingle I. V. Kologrivova
Ye. N. Kologrivova
T. Ye. Suslova
Molecular aspects of the T-helpers type 17 functioning
Бюллетень сибирской медицины
t helper type 17
cytokines
immune regulation
title Molecular aspects of the T-helpers type 17 functioning
title_full Molecular aspects of the T-helpers type 17 functioning
title_fullStr Molecular aspects of the T-helpers type 17 functioning
title_full_unstemmed Molecular aspects of the T-helpers type 17 functioning
title_short Molecular aspects of the T-helpers type 17 functioning
title_sort molecular aspects of the t helpers type 17 functioning
topic t helper type 17
cytokines
immune regulation
url https://bulletin.ssmu.ru/jour/article/view/1435
work_keys_str_mv AT ivkologrivova molecularaspectsofthethelperstype17functioning
AT yenkologrivova molecularaspectsofthethelperstype17functioning
AT tyesuslova molecularaspectsofthethelperstype17functioning