Lurasidone induces developmental toxicity and behavioral impairments in zebrafish embryos

Lurasidone induces developmental toxicity and behavioral impairments in zebrafish embryos

IntroductionLurasidone, a second-generation antipsychotic widely used for schizophrenia and bipolar disorder due to its favorable metabolic profile, has poorly understood potential developmental neurotoxicity. This study investigated its effects on zebrafish embryos to address this gap.MethodsZebraf...

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Bibliographic Details
Main Authors: Wentian Li, Fang Wang, Zhe Feng, Qianqian Cheng, Yuqing Huang, Lisheng Zhu, Han Xiao, Hongjian Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Psychiatry
Subjects:
lurasidone
neurotoxicity
zebrafish embryo model
neurotransmitter systems
behavioral toxicology
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1581524/full
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