Circumcision in patients with bleeding disorders: Can it be done safely?

ABSTRACT Purpose: The purpose of our study was to review outcome of circumcision among children with bleeding disorders at our institution and also to determine the impact of optimization leading to safe circumcision. Methods: Data representing boys (age 0-16 years) who underwent routine circ...

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Main Authors: Huma Faiz Halepota, Ahmad Vaqas Faruque, Muhammad Arshad
Format: Article
Language:English
Published: Bahria Univerisy Health Sciences, Campus Karachi 2018-06-01
Series:Journal of Bahria University Medical and Dental College
Subjects:
Online Access:https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/308
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author Huma Faiz Halepota
Ahmad Vaqas Faruque
Muhammad Arshad
author_facet Huma Faiz Halepota
Ahmad Vaqas Faruque
Muhammad Arshad
author_sort Huma Faiz Halepota
collection DOAJ
description ABSTRACT Purpose: The purpose of our study was to review outcome of circumcision among children with bleeding disorders at our institution and also to determine the impact of optimization leading to safe circumcision. Methods: Data representing boys (age 0-16 years) who underwent routine circumcision at the Aga Khan University Hospital (AKUH) between1988-2014 was retrospectively reviewed. Children with bleeding disorder   were identified using International Classification of Diseases (ICD) Code 64.0.  Data was retrieved and confidentially was maintained.  SPSS version 19 was used for statistical analysis. Results: During 26 years 13,200 circumcisions were performed at AKUH.  Amongst these 8,463 (64.11%) were done by using Plastibell, while 4,737 (35.88%) by open slit method.  Only 23 (0.17%) children were identified with bleeding disorder.  Two groups were made, Group-A (n:15) children with known bleeding disorders having circumcision and Group-B, (n:8) those in whom bleeding disorder was diagnosed after circumcision. Median age of children in Group-A was 9 years. All children in Group-A underwent open circumcision. 10 patients had Factor VIII deficiency, 2 had Glanzmann’s thrombasthenia, 1 had Factor IX deficiency, 1 had Quebec platelet disorder, and 1 had Von Willebrand disorder.  Median age of children in Group-B was 3 months. 7 out of 8 underwent plastibell while one had circumcision by open technique. 7 were diagnosed as Factor VIII deficiency and 1 diagnosed later to have Glanzmann's thrombasthenia. Statistical analysis showed significant difference among these two groups’ p-value with respect to age (p-value 0.00) and family history (p-value 0.04- Fisher’s exact test).  Both groups had similar postoperative length of stay. Overall bleeding complication rate after optimization was 13.33%. Conclusion: With the help of hematologist and adequate Factor replacement, these children can be managed as daycare.  We suggest risks and benefit should be discussed with parents before procedure.
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spelling doaj-art-4823b5d7c0dc4fa18fe753ec709cb80f2025-08-20T02:45:03ZengBahria Univerisy Health Sciences, Campus KarachiJournal of Bahria University Medical and Dental College2220-75622617-94822018-06-018210.51985/JBUMDC2018003Circumcision in patients with bleeding disorders: Can it be done safely?Huma Faiz HalepotaAhmad Vaqas FaruqueMuhammad Arshad ABSTRACT Purpose: The purpose of our study was to review outcome of circumcision among children with bleeding disorders at our institution and also to determine the impact of optimization leading to safe circumcision. Methods: Data representing boys (age 0-16 years) who underwent routine circumcision at the Aga Khan University Hospital (AKUH) between1988-2014 was retrospectively reviewed. Children with bleeding disorder   were identified using International Classification of Diseases (ICD) Code 64.0.  Data was retrieved and confidentially was maintained.  SPSS version 19 was used for statistical analysis. Results: During 26 years 13,200 circumcisions were performed at AKUH.  Amongst these 8,463 (64.11%) were done by using Plastibell, while 4,737 (35.88%) by open slit method.  Only 23 (0.17%) children were identified with bleeding disorder.  Two groups were made, Group-A (n:15) children with known bleeding disorders having circumcision and Group-B, (n:8) those in whom bleeding disorder was diagnosed after circumcision. Median age of children in Group-A was 9 years. All children in Group-A underwent open circumcision. 10 patients had Factor VIII deficiency, 2 had Glanzmann’s thrombasthenia, 1 had Factor IX deficiency, 1 had Quebec platelet disorder, and 1 had Von Willebrand disorder.  Median age of children in Group-B was 3 months. 7 out of 8 underwent plastibell while one had circumcision by open technique. 7 were diagnosed as Factor VIII deficiency and 1 diagnosed later to have Glanzmann's thrombasthenia. Statistical analysis showed significant difference among these two groups’ p-value with respect to age (p-value 0.00) and family history (p-value 0.04- Fisher’s exact test).  Both groups had similar postoperative length of stay. Overall bleeding complication rate after optimization was 13.33%. Conclusion: With the help of hematologist and adequate Factor replacement, these children can be managed as daycare.  We suggest risks and benefit should be discussed with parents before procedure. https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/308Bleeding, circumcision, hemophiliacs
spellingShingle Huma Faiz Halepota
Ahmad Vaqas Faruque
Muhammad Arshad
Circumcision in patients with bleeding disorders: Can it be done safely?
Journal of Bahria University Medical and Dental College
Bleeding, circumcision, hemophiliacs
title Circumcision in patients with bleeding disorders: Can it be done safely?
title_full Circumcision in patients with bleeding disorders: Can it be done safely?
title_fullStr Circumcision in patients with bleeding disorders: Can it be done safely?
title_full_unstemmed Circumcision in patients with bleeding disorders: Can it be done safely?
title_short Circumcision in patients with bleeding disorders: Can it be done safely?
title_sort circumcision in patients with bleeding disorders can it be done safely
topic Bleeding, circumcision, hemophiliacs
url https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/308
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