Early Screening and Identification of an Asymptomatic Pheochromocytoma in a Child with Von Hippel-Lindau: A Case Report

Introduction: Von Hippel-Lindau (VHL) is a diagnosis that leads to increased risk of tumor development over the course of a patient’s lifetime. Patients with VHL undergo screening for multiple tumor types, including pheochromocytomas (PCCs). There is variability among the different intern...

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Main Authors: Kristine Schmeling, Jennifer Schuh, Dave Lal, Kerri Becktell
Format: Article
Language:English
Published: Karger Publishers 2024-11-01
Series:Case Reports in Oncology
Online Access:https://karger.com/article/doi/10.1159/000541527
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author Kristine Schmeling
Jennifer Schuh
Dave Lal
Kerri Becktell
author_facet Kristine Schmeling
Jennifer Schuh
Dave Lal
Kerri Becktell
author_sort Kristine Schmeling
collection DOAJ
description Introduction: Von Hippel-Lindau (VHL) is a diagnosis that leads to increased risk of tumor development over the course of a patient’s lifetime. Patients with VHL undergo screening for multiple tumor types, including pheochromocytomas (PCCs). There is variability among the different international guidelines regarding the age to begin PCC screening, with most suggesting 5 years for screening initiation. Case Presentation: Our patient is a 4-year-old female who underwent screening for PCC at the time of her VHL diagnosis while asymptomatic that identified a unilateral PCC. This was amendable to treatment with laparoscopic partial adrenalectomy. Conclusion: This is the first report of an asymptomatic PCC being identified in a patient under the age of 5. With early identification, this was treated surgically before it caused systemic symptoms with preservation of normal adrenal gland tissue. This supports adhering to the pediatric specific guidelines which recommend earlier initiation of PCC screening in pediatric patients with VHL.
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spelling doaj-art-481d869b7ab842d2bb62c1840ccdb6d92025-08-20T01:51:01ZengKarger PublishersCase Reports in Oncology1662-65752024-11-011711309131510.1159/000541527541527Early Screening and Identification of an Asymptomatic Pheochromocytoma in a Child with Von Hippel-Lindau: A Case ReportKristine SchmelingJennifer SchuhDave LalKerri Becktell Introduction: Von Hippel-Lindau (VHL) is a diagnosis that leads to increased risk of tumor development over the course of a patient’s lifetime. Patients with VHL undergo screening for multiple tumor types, including pheochromocytomas (PCCs). There is variability among the different international guidelines regarding the age to begin PCC screening, with most suggesting 5 years for screening initiation. Case Presentation: Our patient is a 4-year-old female who underwent screening for PCC at the time of her VHL diagnosis while asymptomatic that identified a unilateral PCC. This was amendable to treatment with laparoscopic partial adrenalectomy. Conclusion: This is the first report of an asymptomatic PCC being identified in a patient under the age of 5. With early identification, this was treated surgically before it caused systemic symptoms with preservation of normal adrenal gland tissue. This supports adhering to the pediatric specific guidelines which recommend earlier initiation of PCC screening in pediatric patients with VHL. https://karger.com/article/doi/10.1159/000541527
spellingShingle Kristine Schmeling
Jennifer Schuh
Dave Lal
Kerri Becktell
Early Screening and Identification of an Asymptomatic Pheochromocytoma in a Child with Von Hippel-Lindau: A Case Report
Case Reports in Oncology
title Early Screening and Identification of an Asymptomatic Pheochromocytoma in a Child with Von Hippel-Lindau: A Case Report
title_full Early Screening and Identification of an Asymptomatic Pheochromocytoma in a Child with Von Hippel-Lindau: A Case Report
title_fullStr Early Screening and Identification of an Asymptomatic Pheochromocytoma in a Child with Von Hippel-Lindau: A Case Report
title_full_unstemmed Early Screening and Identification of an Asymptomatic Pheochromocytoma in a Child with Von Hippel-Lindau: A Case Report
title_short Early Screening and Identification of an Asymptomatic Pheochromocytoma in a Child with Von Hippel-Lindau: A Case Report
title_sort early screening and identification of an asymptomatic pheochromocytoma in a child with von hippel lindau a case report
url https://karger.com/article/doi/10.1159/000541527
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