Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironment

Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironment

Abstract High-grade serous ovarian cancer (HGSOC) is marked by significant molecular diversity, presenting a major clinical challenge due to its aggressive nature and poor prognosis. This study aims to deepen the understanding of HGSOC by characterizing mRNA subtypes and examining their immune micro...

Full description

Saved in:
Bibliographic Details
Main Authors: Kaylin M. Carey, Corey D. Young, Alexis J. Clark, Eric B. Dammer, Rajesh Singh, James W. Lillard
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Ovarian Research
Subjects:
High-grade serous ovarian cancer
Immune microenvironment
Transcriptomic subtypes
Gene expression
Patient outcomes
Online Access:https://doi.org/10.1186/s13048-024-01556-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items