Single-cell RNA-sequencing of circulating eosinophils from asthma patients reveals an inflammatory signature

Single-cell RNA-sequencing of circulating eosinophils from asthma patients reveals an inflammatory signature

Summary: Asthma is the most common chronic lung disorder in the United States. While asthma is heterogeneous, blood eosinophils are central to the pathogenesis in most cases. Yet, the power of modern omics has not been widely applied to the study of asthma eosinophils. We report single cell RNA sequ...

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Bibliographic Details
Main Authors: Kyndal Goss, Melanie L. Grant, Cherish Caldwell, Gail A. Dallalio, Susan T. Stephenson, Anne M. Fitzpatrick, Edwin M. Horwitz
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
Subjects:
Health sciences
Medicine
Medical specialty
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225008703
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