An Examination of the Ethnobotanical, Phytochemical, Antimicrobial, and Biological Properties of <i>Zygophyllum coccineum</i>, Emphasizing Its Potential as a Valuable Forage Shrub
The growing issue of antimicrobial resistance poses a significant challenge for microbiological research, driving the need for alternative antibiotics with minimal side effects. <i>Zygophyllum coccineum</i>, commonly referred to as “Tebtab” in Arabic and “Red Spinepod” in English, has tr...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-04-01
|
| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/15/4/661 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The growing issue of antimicrobial resistance poses a significant challenge for microbiological research, driving the need for alternative antibiotics with minimal side effects. <i>Zygophyllum coccineum</i>, commonly referred to as “Tebtab” in Arabic and “Red Spinepod” in English, has traditionally been utilized as forage for camels and ruminants. While its antimicrobial activity against human pathogens has been documented, its efficacy against animal pathogens remains underexplored. This study aims to evaluate the phytochemical composition, biological activities, and antimicrobial potential of water and organic-solvent extracts of <i>Zygophyllum coccineum</i> against a range of reference microbial strains and animal pathogens. The findings revealed that all extracts exhibited notable antimicrobial, antioxidant, and cytotoxic activities attributed to their bioactive constituents. Among them, the ethyl acetate extract displayed the strongest antimicrobial effects against bacterial and fungal strains. Additionally, this extract demonstrated the highest antioxidant capacity and showed promising cytotoxic activity against lung (A549) and breast (MCF-7) cancer cell lines. These results underscore the potential of <i>Zygophyllum coccineum</i> as a valuable natural resource for developing antimicrobial, antioxidant, and cytotoxic therapies for applications in both human and veterinary medicine. |
|---|---|
| ISSN: | 2075-1729 |