Inhibition of human gastric cancer growth by cytokine-induced killer cells plus chemotherapy with or without cadonilimab in a mouse xenograft tumor model

Inhibition of human gastric cancer growth by cytokine-induced killer cells plus chemotherapy with or without cadonilimab in a mouse xenograft tumor model

BackgroundCytokine-induced killer (CIK) cell therapy has shown potent antitumor cytotoxicity. To date, no study has evaluated the efficacy and safety of combining CIK cell therapy with chemotherapy, with or without the immune checkpoint inhibitor (ICI) cadonilimab, for treating gastric cancer (GC).M...

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Bibliographic Details
Main Authors: Wenwei Yang, Jingwei Liu, Tiantian Hou, Xu Lu, Lin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
gastric cancer
cytokine-induced killer cells
immune checkpoint inhibitors
chemotherapy
combination therapy
mouse xenograft model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1609320/full
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