Short-Term Relationship Between Air Pollution and Mortality from Respiratory and Cardiovascular Diseases in China, 2008–2020

Most existing epidemiological studies on the impact of air pollution on noncommunicable diseases have focused on urban areas, rather than nationwide studies that include rural areas. This study utilized a time-stratified case-crossover study that included deaths registered in the National Mortality...

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Main Authors: Yunning Liu, Xuyang Shan, Yitong Sun, Xinpeng Guan, Lijun Wang, Xinghou He, Jiangmei Liu, Jinling You, Rongshan Wu, Jianbin Wu, Bin Zhang, Jinlei Qi, Peng Yin, Mengyao Li, Xinghua He, Zifa Wang, Hongbing Xu, Jing Wu, Wei Huang
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Toxics
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Online Access:https://www.mdpi.com/2305-6304/13/3/156
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author Yunning Liu
Xuyang Shan
Yitong Sun
Xinpeng Guan
Lijun Wang
Xinghou He
Jiangmei Liu
Jinling You
Rongshan Wu
Jianbin Wu
Bin Zhang
Jinlei Qi
Peng Yin
Mengyao Li
Xinghua He
Zifa Wang
Hongbing Xu
Jing Wu
Wei Huang
author_facet Yunning Liu
Xuyang Shan
Yitong Sun
Xinpeng Guan
Lijun Wang
Xinghou He
Jiangmei Liu
Jinling You
Rongshan Wu
Jianbin Wu
Bin Zhang
Jinlei Qi
Peng Yin
Mengyao Li
Xinghua He
Zifa Wang
Hongbing Xu
Jing Wu
Wei Huang
author_sort Yunning Liu
collection DOAJ
description Most existing epidemiological studies on the impact of air pollution on noncommunicable diseases have focused on urban areas, rather than nationwide studies that include rural areas. This study utilized a time-stratified case-crossover study that included deaths registered in the National Mortality Surveillance System from 2008 to 2020. Atmospheric particulate matter (PM<sub>10</sub> and PM<sub>2.5</sub>), nitrogen dioxide (NO<sub>2</sub>), sulfur dioxide (SO<sub>2</sub>), and carbon monoxide (CO) were evaluated via the National Nested Air Quality Prediction Modeling System. Conditional logistic regression was used to assess the associations between short-term air pollution exposure and the risk of respiratory disease and cardiovascular disease (CVD) mortality. There were increases in the risk of respiratory diseases (0.12%, 0.10%, 0.10%, 0.05%, and 0.40%) and CVDs (0.08%, 0.07%, 0.03%, 0.02%, and 0.22%) for each 10 μg/m<sup>3</sup> increase in the concentrations of PM<sub>10</sub>, PM<sub>2.5</sub>, NO<sub>2</sub>, and SO<sub>2</sub>, respectively, and for each 1 mg/m<sup>3</sup> increase in the concentration of CO, which may be associated with the participants’ characteristics. The results of these national analyses indicate that ambient air pollutants are significantly associated with increased risks of respiratory disease and CVD death in both urban and rural areas, which is critical for air pollution control, especially in low- and middle-income areas.
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spelling doaj-art-47f1a31f983d4d1da9166b9acab5c64a2025-08-20T01:48:46ZengMDPI AGToxics2305-63042025-02-0113315610.3390/toxics13030156Short-Term Relationship Between Air Pollution and Mortality from Respiratory and Cardiovascular Diseases in China, 2008–2020Yunning Liu0Xuyang Shan1Yitong Sun2Xinpeng Guan3Lijun Wang4Xinghou He5Jiangmei Liu6Jinling You7Rongshan Wu8Jianbin Wu9Bin Zhang10Jinlei Qi11Peng Yin12Mengyao Li13Xinghua He14Zifa Wang15Hongbing Xu16Jing Wu17Wei Huang18National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaDepartment of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing 100191, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaDepartment of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing 100191, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaDepartment of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing 100191, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaState Key Laboratory of Environmental Criteria and Risk Assessment, State Environmental Protection Key Laboratory of Ecological Effect and Risk Assessment of Chemicals, Chinese Research Academy of Environmental Sciences, Beijing 100012, ChinaSchool of Geography, Nanjing Normal University, Nanjing 210023, ChinaDepartment of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing 100191, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaDepartment of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing 100191, ChinaSchool of Geography, Nanjing Normal University, Nanjing 210023, ChinaState Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, ChinaDepartment of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing 100191, ChinaNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaDepartment of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing 100191, ChinaMost existing epidemiological studies on the impact of air pollution on noncommunicable diseases have focused on urban areas, rather than nationwide studies that include rural areas. This study utilized a time-stratified case-crossover study that included deaths registered in the National Mortality Surveillance System from 2008 to 2020. Atmospheric particulate matter (PM<sub>10</sub> and PM<sub>2.5</sub>), nitrogen dioxide (NO<sub>2</sub>), sulfur dioxide (SO<sub>2</sub>), and carbon monoxide (CO) were evaluated via the National Nested Air Quality Prediction Modeling System. Conditional logistic regression was used to assess the associations between short-term air pollution exposure and the risk of respiratory disease and cardiovascular disease (CVD) mortality. There were increases in the risk of respiratory diseases (0.12%, 0.10%, 0.10%, 0.05%, and 0.40%) and CVDs (0.08%, 0.07%, 0.03%, 0.02%, and 0.22%) for each 10 μg/m<sup>3</sup> increase in the concentrations of PM<sub>10</sub>, PM<sub>2.5</sub>, NO<sub>2</sub>, and SO<sub>2</sub>, respectively, and for each 1 mg/m<sup>3</sup> increase in the concentration of CO, which may be associated with the participants’ characteristics. The results of these national analyses indicate that ambient air pollutants are significantly associated with increased risks of respiratory disease and CVD death in both urban and rural areas, which is critical for air pollution control, especially in low- and middle-income areas.https://www.mdpi.com/2305-6304/13/3/156short-termair pollutionrespiratory diseasesCVDsmortalitycase crossover study
spellingShingle Yunning Liu
Xuyang Shan
Yitong Sun
Xinpeng Guan
Lijun Wang
Xinghou He
Jiangmei Liu
Jinling You
Rongshan Wu
Jianbin Wu
Bin Zhang
Jinlei Qi
Peng Yin
Mengyao Li
Xinghua He
Zifa Wang
Hongbing Xu
Jing Wu
Wei Huang
Short-Term Relationship Between Air Pollution and Mortality from Respiratory and Cardiovascular Diseases in China, 2008–2020
Toxics
short-term
air pollution
respiratory diseases
CVDs
mortality
case crossover study
title Short-Term Relationship Between Air Pollution and Mortality from Respiratory and Cardiovascular Diseases in China, 2008–2020
title_full Short-Term Relationship Between Air Pollution and Mortality from Respiratory and Cardiovascular Diseases in China, 2008–2020
title_fullStr Short-Term Relationship Between Air Pollution and Mortality from Respiratory and Cardiovascular Diseases in China, 2008–2020
title_full_unstemmed Short-Term Relationship Between Air Pollution and Mortality from Respiratory and Cardiovascular Diseases in China, 2008–2020
title_short Short-Term Relationship Between Air Pollution and Mortality from Respiratory and Cardiovascular Diseases in China, 2008–2020
title_sort short term relationship between air pollution and mortality from respiratory and cardiovascular diseases in china 2008 2020
topic short-term
air pollution
respiratory diseases
CVDs
mortality
case crossover study
url https://www.mdpi.com/2305-6304/13/3/156
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