Human Thyroid Cancer-1 (TC-1) is a vertebrate specific oncogenic protein that protects against copper and pro-apoptotic genes in yeast

Human Thyroid Cancer-1 (TC-1) is a vertebrate specific oncogenic protein that protects against copper and pro-apoptotic genes in yeast

The human Thyroid Cancer-1 (hTC-1) protein, also known as C8orf4 was initially identified as a gene that was up-regulated in human thyroid cancer. Here we show that hTC-1 is a peptide that prevents the effects of over-expressing Bax in yeast. Analysis of the 106 residues of hTC-1 in available...

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Bibliographic Details
Main Authors: Natalie K. Jones, Nagla T.T. Arab, Rawan Eid, Nada Gharib, Sara Sheiban, Hojatollah Vali, Chamel Khoury, Alistair Murray, Eric Boucher, Craig A. Mandato, Paul G. Young, Michael T. Greenwood
Format: Article
Language:English
Published: Shared Science Publishers OG 2015-07-01
Series:Microbial Cell
Subjects:
TC-1
apoptosis
cell death
anti-apoptotic
cell survival
cancer
yeast
Online Access:http://microbialcell.com/researcharticles/human-thyroid-cancer-1-tc-1-is-a-vertebrate-specific-oncogenic-protein-that-protects-against-copper-and-pro-apoptotic-genes-in-yeast/
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