Liver actinomycosis mimicking liver tumor

Background. The liver actinomycosis is a rare disease associated with complex differentiation from the liver metastases or hepatocellular carcinoma. Case report. A 50-year old immunocompetent female patient was admitted to the Surgical Department in an exhausted condition, with dyspnea, significant...

Full description

Saved in:
Bibliographic Details
Main Authors: Ćulafić Đorđe M., Lekić Nebojša S., Kerkez Mirko D., Mijač Dragana D.
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2009-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500911924C.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850182069965029376
author Ćulafić Đorđe M.
Lekić Nebojša S.
Kerkez Mirko D.
Mijač Dragana D.
author_facet Ćulafić Đorđe M.
Lekić Nebojša S.
Kerkez Mirko D.
Mijač Dragana D.
author_sort Ćulafić Đorđe M.
collection DOAJ
description Background. The liver actinomycosis is a rare disease associated with complex differentiation from the liver metastases or hepatocellular carcinoma. Case report. A 50-year old immunocompetent female patient was admitted to the Surgical Department in an exhausted condition, with dyspnea, significant weight loss and intermittent fever in the recent two months. Diagnostic procedures that followed, including abdominal ultrasound and computed tomography led us to the diagnosis of metastatic liver disease of unknown etiology with pleural and pericardial effusion. Intraoperatively, the presence of liver pseudotumor without malignancy in the liver was confirmed. Histological examination confirmed the diagnosis of liver actinomycosis. Prolonged treatment with high dose penicillin was performed and all signs and symptoms resolved completely without further problems. The control abdominal ultrasound finding was normal. Conclusion. Liver actinomycosis has a nonspecific presentation, often mimicking liver tumor. A timely diagnosis as well as a combined surgical and antibiotic therapy is necessary in the treatment of patients with primary disease and prevention of complications.
format Article
id doaj-art-47e61a76f68b4c829b6543b4fc15c621
institution OA Journals
issn 0042-8450
language English
publishDate 2009-01-01
publisher Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
record_format Article
series Vojnosanitetski Pregled
spelling doaj-art-47e61a76f68b4c829b6543b4fc15c6212025-08-20T02:17:46ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502009-01-01661192492710.2298/VSP0911924CLiver actinomycosis mimicking liver tumorĆulafić Đorđe M.Lekić Nebojša S.Kerkez Mirko D.Mijač Dragana D.Background. The liver actinomycosis is a rare disease associated with complex differentiation from the liver metastases or hepatocellular carcinoma. Case report. A 50-year old immunocompetent female patient was admitted to the Surgical Department in an exhausted condition, with dyspnea, significant weight loss and intermittent fever in the recent two months. Diagnostic procedures that followed, including abdominal ultrasound and computed tomography led us to the diagnosis of metastatic liver disease of unknown etiology with pleural and pericardial effusion. Intraoperatively, the presence of liver pseudotumor without malignancy in the liver was confirmed. Histological examination confirmed the diagnosis of liver actinomycosis. Prolonged treatment with high dose penicillin was performed and all signs and symptoms resolved completely without further problems. The control abdominal ultrasound finding was normal. Conclusion. Liver actinomycosis has a nonspecific presentation, often mimicking liver tumor. A timely diagnosis as well as a combined surgical and antibiotic therapy is necessary in the treatment of patients with primary disease and prevention of complications.http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500911924C.pdfactinomycosisliver neoplasmsgranulomaplasma celldiagnosis, differentialtherapeutics
spellingShingle Ćulafić Đorđe M.
Lekić Nebojša S.
Kerkez Mirko D.
Mijač Dragana D.
Liver actinomycosis mimicking liver tumor
Vojnosanitetski Pregled
actinomycosis
liver neoplasms
granuloma
plasma cell
diagnosis, differential
therapeutics
title Liver actinomycosis mimicking liver tumor
title_full Liver actinomycosis mimicking liver tumor
title_fullStr Liver actinomycosis mimicking liver tumor
title_full_unstemmed Liver actinomycosis mimicking liver tumor
title_short Liver actinomycosis mimicking liver tumor
title_sort liver actinomycosis mimicking liver tumor
topic actinomycosis
liver neoplasms
granuloma
plasma cell
diagnosis, differential
therapeutics
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500911924C.pdf
work_keys_str_mv AT culaficđorđem liveractinomycosismimickinglivertumor
AT lekicnebojsas liveractinomycosismimickinglivertumor
AT kerkezmirkod liveractinomycosismimickinglivertumor
AT mijacdraganad liveractinomycosismimickinglivertumor