Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells
Background Limited activation and infiltration of CD8+ T cells are major challenges facing T cell-based immunotherapy for most solid tumors, of which the mechanism is multilayered and not yet fully understood.Methods Levels of CD93 expression on monocytes from paired non-tumor, peritumor and tumor t...
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| Main Authors: | Yan Wu, Da Jiang, Xing-Chen Liu, Yong-Hao Ruan, Limin Zheng, Aiqi Huang, Bai-Xi Zhu, Jiangling Gong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2024-10-01
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| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/12/10/e010148.full |
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