TLR4 Signaling in MPP+-Induced Activation of BV-2 Cells

Aims. This work was conducted to establish an in vitro Parkinson’s disease (PD) model by exposing BV-2 cells to 1-methyl-4-phenylpyridinium (MPP+) and exploring the roles of TLR2/TLR4/TLR9 in inflammatory responses to MPP+. Methods/Results. MTT assay showed that cell viability of BV-2 cells was 84.7...

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Bibliographic Details
Main Authors: Peng Zhou, Ruihui Weng, Zhaoyu Chen, Rui Wang, Jing Zou, Xu Liu, Jinchi Liao, Yanping Wang, Ying Xia, Qing Wang
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2016/5076740
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