Lung Cancer Prediction Using an Enhanced Neutrosophic Set Combined with a Machine Learning Approach

Lung cancer (LC) remains one of the most lethal diseases globally, necessitating the development of advanced predictive models for early detection and accurate diagnosis. Traditional classification techniques often struggle with uncertainty and indeterminacy in medical data, which can lead to misdia...

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Main Authors: Vakeel A. Khan, Asheesh Kumar Yadav, Mohammad Arshad, Nadeem Akhtar
Format: Article
Language:English
Published: University of New Mexico 2025-07-01
Series:Neutrosophic Sets and Systems
Subjects:
Online Access:https://fs.unm.edu/NSS/64LungCancer.pdf
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author Vakeel A. Khan
Asheesh Kumar Yadav
Mohammad Arshad
Nadeem Akhtar
author_facet Vakeel A. Khan
Asheesh Kumar Yadav
Mohammad Arshad
Nadeem Akhtar
author_sort Vakeel A. Khan
collection DOAJ
description Lung cancer (LC) remains one of the most lethal diseases globally, necessitating the development of advanced predictive models for early detection and accurate diagnosis. Traditional classification techniques often struggle with uncertainty and indeterminacy in medical data, which can lead to misdiagnosis and reduced diagnostic reliability. To address this issue, we propose an Enhanced Neutrosophic Set (ENS) framework integrated with machine learning algorithms to improve the prediction accuracy of lung cancer. Neutrosophic Set (NS) theory extends classical and fuzzy logic by introducing three independent membership components: truth, indeterminacy, and falsity, which enable more effective modeling of uncertainty in clinical datasets. The proposed ENS model enhances decision-making by optimizing feature selection and minimizing ambiguity in patient data representation. We apply machine learning classifiers including Logistic Regression (LR), KNearest Neighbors (KNN), and Random Forest (RF) to evaluate the performance of the ENS-transformed dataset in predicting lung cancer risk. Experimental results indicate that the ENS-based models outperform traditional approaches in terms of classification accuracy, sensitivity, and specificity. This study demonstrates the effectiveness of neutrosophic-based AI frameworks in medical diagnostics and highlights their potential in developing reliable, early detection systems for lung cancer and other critical diseases.
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spelling doaj-art-47dcf8b8b49741b5a422407b5bff488e2025-08-20T03:44:18ZengUniversity of New MexicoNeutrosophic Sets and Systems2331-60552331-608X2025-07-018897398710.5281/zenodo.15878877Lung Cancer Prediction Using an Enhanced Neutrosophic Set Combined with a Machine Learning ApproachVakeel A. KhanAsheesh Kumar YadavMohammad Arshad Nadeem AkhtarLung cancer (LC) remains one of the most lethal diseases globally, necessitating the development of advanced predictive models for early detection and accurate diagnosis. Traditional classification techniques often struggle with uncertainty and indeterminacy in medical data, which can lead to misdiagnosis and reduced diagnostic reliability. To address this issue, we propose an Enhanced Neutrosophic Set (ENS) framework integrated with machine learning algorithms to improve the prediction accuracy of lung cancer. Neutrosophic Set (NS) theory extends classical and fuzzy logic by introducing three independent membership components: truth, indeterminacy, and falsity, which enable more effective modeling of uncertainty in clinical datasets. The proposed ENS model enhances decision-making by optimizing feature selection and minimizing ambiguity in patient data representation. We apply machine learning classifiers including Logistic Regression (LR), KNearest Neighbors (KNN), and Random Forest (RF) to evaluate the performance of the ENS-transformed dataset in predicting lung cancer risk. Experimental results indicate that the ENS-based models outperform traditional approaches in terms of classification accuracy, sensitivity, and specificity. This study demonstrates the effectiveness of neutrosophic-based AI frameworks in medical diagnostics and highlights their potential in developing reliable, early detection systems for lung cancer and other critical diseases. https://fs.unm.edu/NSS/64LungCancer.pdflung cancer predictionenhanced neutrosophic setmachine learningmedical diagnosisuncertainty modelingrandom forestlogistic regressionk-nearest neighborsneutrosophic logicclinical data analysis
spellingShingle Vakeel A. Khan
Asheesh Kumar Yadav
Mohammad Arshad
Nadeem Akhtar
Lung Cancer Prediction Using an Enhanced Neutrosophic Set Combined with a Machine Learning Approach
Neutrosophic Sets and Systems
lung cancer prediction
enhanced neutrosophic set
machine learning
medical diagnosis
uncertainty modeling
random forest
logistic regression
k-nearest neighbors
neutrosophic logic
clinical data analysis
title Lung Cancer Prediction Using an Enhanced Neutrosophic Set Combined with a Machine Learning Approach
title_full Lung Cancer Prediction Using an Enhanced Neutrosophic Set Combined with a Machine Learning Approach
title_fullStr Lung Cancer Prediction Using an Enhanced Neutrosophic Set Combined with a Machine Learning Approach
title_full_unstemmed Lung Cancer Prediction Using an Enhanced Neutrosophic Set Combined with a Machine Learning Approach
title_short Lung Cancer Prediction Using an Enhanced Neutrosophic Set Combined with a Machine Learning Approach
title_sort lung cancer prediction using an enhanced neutrosophic set combined with a machine learning approach
topic lung cancer prediction
enhanced neutrosophic set
machine learning
medical diagnosis
uncertainty modeling
random forest
logistic regression
k-nearest neighbors
neutrosophic logic
clinical data analysis
url https://fs.unm.edu/NSS/64LungCancer.pdf
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AT asheeshkumaryadav lungcancerpredictionusinganenhancedneutrosophicsetcombinedwithamachinelearningapproach
AT mohammadarshad lungcancerpredictionusinganenhancedneutrosophicsetcombinedwithamachinelearningapproach
AT nadeemakhtar lungcancerpredictionusinganenhancedneutrosophicsetcombinedwithamachinelearningapproach