A Review of Recent Progress in Synthetic Polymer Surface Coatings for the Prevention of Biofilm Formation

Bacterial adhesion and the subsequent formation of biofilms and biofouling have significant economic and health impacts across all sectors. They are especially impactful in industrial corrosion, healthcare, food processing, agriculture, and waste and drinking water. Synthetic polymers that resist ba...

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Main Authors: Adrienne Shea, Matthew T. Bernards
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/30/13/2710
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author Adrienne Shea
Matthew T. Bernards
author_facet Adrienne Shea
Matthew T. Bernards
author_sort Adrienne Shea
collection DOAJ
description Bacterial adhesion and the subsequent formation of biofilms and biofouling have significant economic and health impacts across all sectors. They are especially impactful in industrial corrosion, healthcare, food processing, agriculture, and waste and drinking water. Synthetic polymers that resist bacterial adhesion are adaptable to a wide range of applications in all of these fields. While there are many bacteria-resistant polymers, some of the best performing include polyethylene glycol (PEG), poly(oxazoline) (POZ), and zwitterionic polymers, with zwitterionic polymers showing the most promise with reductions in bacteria adhesion up to 99% over controls. This review summarizes the demonstrated bacterial resistance performance of these polymer coatings based on literature published over the last ten years. It also identifies the front runners for preventing bacterial adhesion while providing the critical next steps for widespread adoption of this technology.
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series Molecules
spelling doaj-art-47d3d47aa91b49f5a0da812058b068962025-08-20T03:28:29ZengMDPI AGMolecules1420-30492025-06-013013271010.3390/molecules30132710A Review of Recent Progress in Synthetic Polymer Surface Coatings for the Prevention of Biofilm FormationAdrienne Shea0Matthew T. Bernards1Department of Chemical and Biological Engineering, University of Idaho, Moscow, ID 83844, USADepartment of Chemical and Biological Engineering, University of Idaho, Moscow, ID 83844, USABacterial adhesion and the subsequent formation of biofilms and biofouling have significant economic and health impacts across all sectors. They are especially impactful in industrial corrosion, healthcare, food processing, agriculture, and waste and drinking water. Synthetic polymers that resist bacterial adhesion are adaptable to a wide range of applications in all of these fields. While there are many bacteria-resistant polymers, some of the best performing include polyethylene glycol (PEG), poly(oxazoline) (POZ), and zwitterionic polymers, with zwitterionic polymers showing the most promise with reductions in bacteria adhesion up to 99% over controls. This review summarizes the demonstrated bacterial resistance performance of these polymer coatings based on literature published over the last ten years. It also identifies the front runners for preventing bacterial adhesion while providing the critical next steps for widespread adoption of this technology.https://www.mdpi.com/1420-3049/30/13/2710biofilmbiofoulingbacterial adhesionhydrogelspolyampholyteszwitterions
spellingShingle Adrienne Shea
Matthew T. Bernards
A Review of Recent Progress in Synthetic Polymer Surface Coatings for the Prevention of Biofilm Formation
Molecules
biofilm
biofouling
bacterial adhesion
hydrogels
polyampholytes
zwitterions
title A Review of Recent Progress in Synthetic Polymer Surface Coatings for the Prevention of Biofilm Formation
title_full A Review of Recent Progress in Synthetic Polymer Surface Coatings for the Prevention of Biofilm Formation
title_fullStr A Review of Recent Progress in Synthetic Polymer Surface Coatings for the Prevention of Biofilm Formation
title_full_unstemmed A Review of Recent Progress in Synthetic Polymer Surface Coatings for the Prevention of Biofilm Formation
title_short A Review of Recent Progress in Synthetic Polymer Surface Coatings for the Prevention of Biofilm Formation
title_sort review of recent progress in synthetic polymer surface coatings for the prevention of biofilm formation
topic biofilm
biofouling
bacterial adhesion
hydrogels
polyampholytes
zwitterions
url https://www.mdpi.com/1420-3049/30/13/2710
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