Investigation of PPARβ/δ within Human Dental Pulp Cells: A Preliminary In Vitro Study

Investigation of PPARβ/δ within Human Dental Pulp Cells: A Preliminary In Vitro Study

Controlling the inflammatory response to restore tissue homeostasis is a crucial step to maintain tooth vitality after pathogen removal from caries-affected dental tissues. The nuclear peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) is a ligand-activated transcription factor with eme...

Full description

Saved in:

Bibliographic Details
Main Authors:	Caroline L. de Lima, Bruna R. Amorim, Carine Royer, Augusto P. Resende, Maria F. Borin, Francisco A. R. Neves, Ana Carolina Acevedo
Format:	Article
Language:	English
Published:	Wiley 2021-01-01
Series:	PPAR Research
Online Access:	http://dx.doi.org/10.1155/2021/8854921
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Regulation of Cell Proliferation and Differentiation by PPARβ/δ
by: Rolf Müller, et al.
Published: (2008-01-01)

Skin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivo.
by: Katrin Hack, et al.
Published: (2012-01-01)

PPARβ/δ prevents inflammation and fibrosis during diabetic cardiomyopathy
by: Adel Rostami, et al.
Published: (2024-12-01)

NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?
by: Gerardo G. Mackenzie, et al.
Published: (2008-01-01)

Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo
by: Larry G. Higgins, et al.
Published: (2012-01-01)

PPARβ/δ-Interfering Peptide Enhanced Mesenchymal Stromal Cell Immunoregulatory Properties
by: Gautier Tejedor, et al.
Published: (2022-01-01)

Neuroprotective Mechanisms of PPARδ: Modulation of Oxidative Stress and Inflammatory Processes
by: Caroline I. Schnegg, et al.
Published: (2011-01-01)

Involvement of Fatty Acid Binding Protein 5 and PPARβ/δ in Prostate Cancer Cell Growth
by: Elwin Morgan, et al.
Published: (2010-01-01)

Muscle-Specific PPARβ/δ Agonism May Provide Synergistic Benefits with Life Style Modifications
by: Adnan Erol
Published: (2007-01-01)

Activation of β-Adrenoceptors by Dobutamine May Induce a Higher Expression of Peroxisome Proliferator-Activated Receptors δ (PPARδ) in Neonatal Rat Cardiomyocytes
by: Ming-Ting Chou, et al.
Published: (2012-01-01)

PPARβ/δ upregulates the insulin receptor β subunit in skeletal muscle by reducing lysosomal activity and EphB4 levels
by: Jue-Rui Wang, et al.
Published: (2024-12-01)

Identification of a novel PPARβ/δ/miR‐21‐3p axis in UV‐induced skin inflammation
by: Gwendoline Degueurce, et al.
Published: (2016-06-01)

PPARδ as a Metabolic Initiator of Mammary Neoplasia and Immune Tolerance
by: Robert I. Glazer
Published: (2016-01-01)

PPARδ Activity in Cardiovascular Diseases: A Potential Pharmacological Target
by: Angela Tesse, et al.
Published: (2009-01-01)

PPARδ: A Potential Therapeutic Target for the Treatment of Metabolic Hypertension
by: Yanli Jiang, et al.
Published: (2019-01-01)

ECM remodeling by PDGFRβ+ dental pulp stem cells drives angiogenesis and pulp regeneration via integrin signaling
by: Tiankai Di, et al.
Published: (2025-06-01)

Cyanidin-3-O-glucoside enhances GLP-1 secretion via PPARβ/δ-β-catenin-TCF-4 pathway in type 2 diabetes mellitus
by: Xiang Ye, et al.
Published: (2025-05-01)

Dental Pulp Defence and Repair Mechanisms in Dental Caries
by: Jean-Christophe Farges, et al.
Published: (2015-01-01)

Activation of PPARs α, β/δ, and γ Impairs TGF-β1-Induced Collagens' Production and Modulates the TIMP-1/MMPs Balance in Three-Dimensional Cultured Chondrocytes
by: Paul-Emile Poleni, et al.
Published: (2010-01-01)

IL-15 Mediates Mitochondrial Activity through a PPARδ-Dependent-PPARα-Independent Mechanism in Skeletal Muscle Cells
by: Shantaé M. Thornton, et al.
Published: (2016-01-01)

The Hippo-YAP/β-catenin signaling axis coordinates odontogenic differentiation in dental pulp stem cells: Implications for dentin-pulp regeneration
by: Chang Chen, et al.
Published: (2025-01-01)

The Hippo-YAP/β-catenin signaling axis coordinates odontogenic differentiation in dental pulp stem cells: Implications for dentin-pulp regeneration.
by: Chang Chen, et al.
Published: (2025-01-01)

Impact of dental pulp cells-derived small extracellular vesicles on the properties and behavior of dental pulp cells: an in-vitro study
by: Dina A. Hammouda, et al.
Published: (2025-05-01)

PDGF-BB overexpressing dental pulp stem cells improve angiogenesis in dental pulp regeneration
by: Wentao Jiang, et al.
Published: (2025-04-01)

Stage-Dependent Regulation of Dental Pulp Stem Cell Odontogenic Differentiation by Transforming Growth Factor-β1
by: Yu Bai, et al.
Published: (2022-01-01)

Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling
by: Yingyan Wang, et al.
Published: (2021-02-01)

The Effect of Differentiation of Human Dental Pulp Stem Cells to Glial Cells on the Sensory Nerves of the Dental Pulp
by: Yan Liu, et al.
Published: (2024-01-01)

Effects of autologous dental pulp stem cells and mineral trioxide aggregate on exposed dogs’ dental pulp
by: Dalia K. Hemdan, et al.
Published: (2022-03-01)

Wnt-GSK3β/β-Catenin Regulates the Differentiation of Dental Pulp Stem Cells into Bladder Smooth Muscle Cells
by: Wenkai Jiang, et al.
Published: (2019-01-01)

Zur Biosynthese des Cholesterins aus β-Hydroxy-β-methyl-δ-valerolacton
by: O. Isler, et al.
Published: (1957-06-01)

Odontogenic differentiation of dental pulp stem cells by glycogen synthase kinase-3β inhibitory peptides
by: Vidhyashree Rajasekar, et al.
Published: (2025-02-01)

Correction: Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling
by: Yingyan Wang, et al.
Published: (2025-02-01)

Influence of Dental Pulp Harvesting Method on the Viability and Differentiation Capacity of Adult Dental Pulp-Derived Mesenchymal Stem Cells
by: Victor Okada Vendramini, et al.
Published: (2021-01-01)

PPARδ Activation Rescues Pancreatic β-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation
by: Mingming Cao, et al.
Published: (2012-01-01)

Biodentine Counteracts the Aging Process of Human Dental Pulp Stem Cells Through Wnt/β-Catenin Pathway
by: Qi Zhang, et al.
Published: (2025-08-01)

Pharmacological inhibition of Peroxisome Proliferation-Activated Receptor Delta (PPARδ) imparts selective leukemia cell death
by: Yingying Yang, et al.
Published: (2025-07-01)

PPARδ activation acts cooperatively with 3-phosphoinositide-dependent protein kinase-1 to enhance mammary tumorigenesis.
by: Claire B Pollock, et al.
Published: (2011-01-01)

In Vivo Articular Cartilage Regeneration Using Human Dental Pulp Stem Cells Cultured in an Alginate Scaffold: A Preliminary Study
by: Manuel Mata, et al.
Published: (2017-01-01)

Effects of Non-Collagenous Proteins, TGF-β1, and PDGF-BB on Viability and Proliferation of Dental Pulp Stem Cells
by: Fahimeh Sadat Tabatabaei, et al.
Published: (2016-03-01)

VPA Enhances Pulp Regeneration by Regulating LPS-Induced Human Dental Pulp Stem Cells Odontogenic Differentiation
by: Zhihua Wang, et al.
Published: (2025-08-01)