Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal Tuberculosis

Background Thoracolumbar spine constitutes the most common site for spinal tuberculosis. Though the treatment of spinal tuberculosis is antitubercular drugs initially, the patient with neurologic weakness warrants definitive surgical procedure of decompression and stabilization. Even though many inv...

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Main Authors: Susanta Kumar Patro, Biswaranjan Nayak, Balappa Holeppagol Krishnamurthy, Arun Kumar, Debabrata Biswal, Prafulla Kumar Sahoo
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2021-04-01
Series:Indian Journal of Neurosurgery
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1698588
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author Susanta Kumar Patro
Biswaranjan Nayak
Balappa Holeppagol Krishnamurthy
Arun Kumar
Debabrata Biswal
Prafulla Kumar Sahoo
author_facet Susanta Kumar Patro
Biswaranjan Nayak
Balappa Holeppagol Krishnamurthy
Arun Kumar
Debabrata Biswal
Prafulla Kumar Sahoo
author_sort Susanta Kumar Patro
collection DOAJ
description Background Thoracolumbar spine constitutes the most common site for spinal tuberculosis. Though the treatment of spinal tuberculosis is antitubercular drugs initially, the patient with neurologic weakness warrants definitive surgical procedure of decompression and stabilization. Even though many investigators have reported favorable results with anterior decompression and stabilization surgery, due to the increased morbidity and complications, the posterior-only approach with decompression and stabilization has evolved as the operation of choice in recent time. Methods All patients aged between 18 and 70 years with clinically and radiologically proven symptomatic thoracolumbar spinal tuberculosis who failed with conservative treatment for 4 weeks or developed neurologic weakness between the treatments are included in this study. All patients were offered decompression and posterior stabilization with transpedicular screws and rods after explaining the above procedure. Clinical outcome was measured by modified Frankel grading; AIS (American Spinal Injury Association impairment score) grade impairment score; and pain assessment done with visual analog scale (VAS) pre- and postoperatively and at 3, 6, and 9 months of interval. Results The postoperative pain relief, neurologic improvement as per modified Frankel grade, AIS grade, and improvement in erythrocyte sedimentation rate and C-reactive protein were significant as compared with the preoperative status. The surgical interventions thus prove to have adequate relief to the patient and arresting the disease progression. The surgical outcome has very minimal intra- and postoperative complications. Conclusion Single-stage decompression and posterior stabilization in thoracolumbar spinal tuberculosis is safe, effective, and results in good clinical outcome. The advantages of surgery include thorough debridement, decompression, and achievement of spinal stabilization.
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spelling doaj-art-47bb513bd59545e68919b4b05af086862025-08-20T02:17:52ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Neurosurgery2277-954X2277-91672021-04-01100318318910.1055/s-0039-1698588Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal TuberculosisSusanta Kumar Patro0Biswaranjan Nayak1Balappa Holeppagol Krishnamurthy2Arun Kumar3Debabrata Biswal4Prafulla Kumar Sahoo5Department of Neurosurgery, Ispat General Hospital, Rourkela, Odisha, IndiaDepartment of Neurosurgery, AMRI Hospital, Bhubaneswar, Odisha, IndiaDepartment of Neurosurgery, Sri Balaji Institute of Neuroscience and Trauma, Vidyanagar, Hubli, Karnataka, IndiaDepartment of Neurosurgery, Fortis Hospital, Shalimar Bagh, Delhi, IndiaDepartment of Neurosurgery, Apollo Hospital, Bhubaneswar, OdishaDepartment of Neurosurgery, Apollo Hospital, Bhubaneswar, OdishaBackground Thoracolumbar spine constitutes the most common site for spinal tuberculosis. Though the treatment of spinal tuberculosis is antitubercular drugs initially, the patient with neurologic weakness warrants definitive surgical procedure of decompression and stabilization. Even though many investigators have reported favorable results with anterior decompression and stabilization surgery, due to the increased morbidity and complications, the posterior-only approach with decompression and stabilization has evolved as the operation of choice in recent time. Methods All patients aged between 18 and 70 years with clinically and radiologically proven symptomatic thoracolumbar spinal tuberculosis who failed with conservative treatment for 4 weeks or developed neurologic weakness between the treatments are included in this study. All patients were offered decompression and posterior stabilization with transpedicular screws and rods after explaining the above procedure. Clinical outcome was measured by modified Frankel grading; AIS (American Spinal Injury Association impairment score) grade impairment score; and pain assessment done with visual analog scale (VAS) pre- and postoperatively and at 3, 6, and 9 months of interval. Results The postoperative pain relief, neurologic improvement as per modified Frankel grade, AIS grade, and improvement in erythrocyte sedimentation rate and C-reactive protein were significant as compared with the preoperative status. The surgical interventions thus prove to have adequate relief to the patient and arresting the disease progression. The surgical outcome has very minimal intra- and postoperative complications. Conclusion Single-stage decompression and posterior stabilization in thoracolumbar spinal tuberculosis is safe, effective, and results in good clinical outcome. The advantages of surgery include thorough debridement, decompression, and achievement of spinal stabilization.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1698588tuberculosisspinedecompressionposterior fixation
spellingShingle Susanta Kumar Patro
Biswaranjan Nayak
Balappa Holeppagol Krishnamurthy
Arun Kumar
Debabrata Biswal
Prafulla Kumar Sahoo
Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal Tuberculosis
Indian Journal of Neurosurgery
tuberculosis
spine
decompression
posterior fixation
title Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal Tuberculosis
title_full Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal Tuberculosis
title_fullStr Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal Tuberculosis
title_full_unstemmed Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal Tuberculosis
title_short Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal Tuberculosis
title_sort clinical outcome of single stage decompression and posterior stabilization in thoracolumbar spinal tuberculosis
topic tuberculosis
spine
decompression
posterior fixation
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1698588
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