Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demonstration study (ImPrEP)Research in context

Summary: Background: Ongoing implementation of HIV pre-exposure prophylaxis (PrEP) in Latin America should consider lessons learned from implementation projects such as ImPrEP (Brazil/Mexico/Peru, 2018–2021). In this analysis we assessed the effect of variables ascertained in early appointments on...

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Main Authors: Carlos F. Caceres, Heather Pines, Kelika A. Konda, Annick Borquez, Ronaldo Moreira, Iuri Leite, Pedro Amparo, Marcelo Cunha, Thiago S. Torres, Juan V. Guanira, Jean-Pierre Jirón, Brenda Hoagland, Heleen Vermandere, Marcos Benedetti, Hamid Vega, Carlos M. Benites, Cristina Pimenta, Beatriz Grinztejn, Valdiléa Veloso, J. David Urbaez-Brito, Polyana d’Albuquerque, Claudio Palombo, Paulo Ricardo Alencastro, Raquel Keiko de Luca Ito, João L. Benedetti, Fabio V. Maria, Paula M. Luz, Lucilene Freitas, Kim Geraldo, Monica Derrico, Sandro Nazer, Tania Kristic, Renato Girade, Renato Lima, Antônio R. Carvalho, Carla Rocha, Pedro Leite, Marcio Lessa, Marilia Santini-Oliveira, Daniel R.B. Bezerra, Cleo de Oliveira Souza, Jacinto Corrêa, Marcelo Alves, Carolina Souza, Camilla Portugal, Mônica dos Santos Valões, Gabriel Lima Mota, Joyce Alves Gomes, Cynthia Ferreira Lima Falcão, Fernanda Falcão Riberson, Luciano Melo, Talita Andrade Oliveira, Agnaldo Moreira Oliveira Júnior, Bruna Fonseca, Leonor Henriette Lannoy, Ludymilla Anderson Santiago Carlos, João Paulo Cunha, Sonia Maria de Alencastro Coracini, Thiago Oliveira Rodrigues, Emília Regina Scharf Mettrau, Kelly Vieira Meira, Heder Tavares, Ana Paula Nunes Viveiros Valeiras, Taiane Miyake Alves de Carvalho Rocha, Alex Amorim, Patrícia Sabadini, Luiz Gustavo Córdoba, Caio Gusmão, Erika Faustino, Julia Soares da Silva Hansen, Agatha Mirian Cunha, Neuza Uchiyama Nishimura, Jaime Eduardo Flygare Razo Prereira Santos, Aline Barnabé Cano, Willyam Magnum Telles Dias, Magô Tonhon, Tania Regina Rezende, Alex Gomes, Eloá dos Santos Rodrigues, Maria das Dores Aires Carneiro, Alexandre Castilho, Mariana Carvalho, Dulce Diaz-Sosa, Centli Guillen-Diaz-Barriga, Lorena Hernández, Rebeca Robles, Maria Elena Medina-Mora, Marcela González, Ivonne Huerta Icelo, Araczy Martinez Davalos, José Gomez Castro, Luis Obed Ocampo Valdez, Fernanda Ramírez Barajas, Verónica Ruiz González, Galileo Vargas Guadarrama, Israel Macías, Jehovani Tena Sánchez, Juan Pablo Osuna Noriega, H. Rodrigo Moheno M, Jorge M. Bernal Ramírez, Víctor Dante Galicia Juarez, Gerardo Vizcaíno, Francisco Javier Arjona, Gino Calvo, Silver Vargas, Oliver Elorreaga, Ximena Gutierrez, Fernando Olivos, Damaris Caviedes, Daniella Adriazola, Eduardo Juárez, Gabriela Mariño, Jazmin Qquellon, Francesca Vasquez, Jean Pierre Jiron, Sonia Flores, Karen Campos
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Language:English
Published: Elsevier 2025-06-01
Series:The Lancet Regional Health. Americas
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667193X25001085
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author Carlos F. Caceres
Heather Pines
Kelika A. Konda
Annick Borquez
Ronaldo Moreira
Iuri Leite
Pedro Amparo
Marcelo Cunha
Thiago S. Torres
Juan V. Guanira
Jean-Pierre Jirón
Brenda Hoagland
Heleen Vermandere
Marcos Benedetti
Hamid Vega
Carlos M. Benites
Cristina Pimenta
Beatriz Grinztejn
Valdiléa Veloso
J. David Urbaez-Brito
Polyana d’Albuquerque
Claudio Palombo
Paulo Ricardo Alencastro
Raquel Keiko de Luca Ito
João L. Benedetti
Fabio V. Maria
Paula M. Luz
Lucilene Freitas
Kim Geraldo
Monica Derrico
Sandro Nazer
Tania Kristic
Renato Girade
Renato Lima
Antônio R. Carvalho
Carla Rocha
Pedro Leite
Marcio Lessa
Marilia Santini-Oliveira
Daniel R.B. Bezerra
Cleo de Oliveira Souza
Jacinto Corrêa
Marcelo Alves
Carolina Souza
Camilla Portugal
Mônica dos Santos Valões
Gabriel Lima Mota
Joyce Alves Gomes
Cynthia Ferreira Lima Falcão
Fernanda Falcão Riberson
Luciano Melo
Talita Andrade Oliveira
Agnaldo Moreira Oliveira Júnior
Bruna Fonseca
Leonor Henriette Lannoy
Ludymilla Anderson Santiago Carlos
João Paulo Cunha
Sonia Maria de Alencastro Coracini
Thiago Oliveira Rodrigues
Emília Regina Scharf Mettrau
Kelly Vieira Meira
Heder Tavares
Ana Paula Nunes Viveiros Valeiras
Taiane Miyake Alves de Carvalho Rocha
Alex Amorim
Patrícia Sabadini
Luiz Gustavo Córdoba
Caio Gusmão
Erika Faustino
Julia Soares da Silva Hansen
Agatha Mirian Cunha
Neuza Uchiyama Nishimura
Jaime Eduardo Flygare Razo Prereira Santos
Aline Barnabé Cano
Willyam Magnum Telles Dias
Magô Tonhon
Tania Regina Rezende
Alex Gomes
Eloá dos Santos Rodrigues
Maria das Dores Aires Carneiro
Alexandre Castilho
Mariana Carvalho
Dulce Diaz-Sosa
Centli Guillen-Diaz-Barriga
Lorena Hernández
Rebeca Robles
Maria Elena Medina-Mora
Marcela González
Ivonne Huerta Icelo
Araczy Martinez Davalos
José Gomez Castro
Luis Obed Ocampo Valdez
Fernanda Ramírez Barajas
Verónica Ruiz González
Galileo Vargas Guadarrama
Israel Macías
Jehovani Tena Sánchez
Juan Pablo Osuna Noriega
H. Rodrigo Moheno M
Jorge M. Bernal Ramírez
Víctor Dante Galicia Juarez
Gerardo Vizcaíno
Francisco Javier Arjona
Gino Calvo
Silver Vargas
Oliver Elorreaga
Ximena Gutierrez
Fernando Olivos
Damaris Caviedes
Daniella Adriazola
Eduardo Juárez
Gabriela Mariño
Jazmin Qquellon
Francesca Vasquez
Jean Pierre Jiron
Sonia Flores
Karen Campos
author_facet Carlos F. Caceres
Heather Pines
Kelika A. Konda
Annick Borquez
Ronaldo Moreira
Iuri Leite
Pedro Amparo
Marcelo Cunha
Thiago S. Torres
Juan V. Guanira
Jean-Pierre Jirón
Brenda Hoagland
Heleen Vermandere
Marcos Benedetti
Hamid Vega
Carlos M. Benites
Cristina Pimenta
Beatriz Grinztejn
Valdiléa Veloso
J. David Urbaez-Brito
Polyana d’Albuquerque
Claudio Palombo
Paulo Ricardo Alencastro
Raquel Keiko de Luca Ito
João L. Benedetti
Fabio V. Maria
Paula M. Luz
Lucilene Freitas
Kim Geraldo
Monica Derrico
Sandro Nazer
Tania Kristic
Renato Girade
Renato Lima
Antônio R. Carvalho
Carla Rocha
Pedro Leite
Marcio Lessa
Marilia Santini-Oliveira
Daniel R.B. Bezerra
Cleo de Oliveira Souza
Jacinto Corrêa
Marcelo Alves
Carolina Souza
Camilla Portugal
Mônica dos Santos Valões
Gabriel Lima Mota
Joyce Alves Gomes
Cynthia Ferreira Lima Falcão
Fernanda Falcão Riberson
Luciano Melo
Talita Andrade Oliveira
Agnaldo Moreira Oliveira Júnior
Bruna Fonseca
Leonor Henriette Lannoy
Ludymilla Anderson Santiago Carlos
João Paulo Cunha
Sonia Maria de Alencastro Coracini
Thiago Oliveira Rodrigues
Emília Regina Scharf Mettrau
Kelly Vieira Meira
Heder Tavares
Ana Paula Nunes Viveiros Valeiras
Taiane Miyake Alves de Carvalho Rocha
Alex Amorim
Patrícia Sabadini
Luiz Gustavo Córdoba
Caio Gusmão
Erika Faustino
Julia Soares da Silva Hansen
Agatha Mirian Cunha
Neuza Uchiyama Nishimura
Jaime Eduardo Flygare Razo Prereira Santos
Aline Barnabé Cano
Willyam Magnum Telles Dias
Magô Tonhon
Tania Regina Rezende
Alex Gomes
Eloá dos Santos Rodrigues
Maria das Dores Aires Carneiro
Alexandre Castilho
Mariana Carvalho
Dulce Diaz-Sosa
Centli Guillen-Diaz-Barriga
Lorena Hernández
Rebeca Robles
Maria Elena Medina-Mora
Marcela González
Ivonne Huerta Icelo
Araczy Martinez Davalos
José Gomez Castro
Luis Obed Ocampo Valdez
Fernanda Ramírez Barajas
Verónica Ruiz González
Galileo Vargas Guadarrama
Israel Macías
Jehovani Tena Sánchez
Juan Pablo Osuna Noriega
H. Rodrigo Moheno M
Jorge M. Bernal Ramírez
Víctor Dante Galicia Juarez
Gerardo Vizcaíno
Francisco Javier Arjona
Gino Calvo
Silver Vargas
Oliver Elorreaga
Ximena Gutierrez
Fernando Olivos
Damaris Caviedes
Daniella Adriazola
Eduardo Juárez
Gabriela Mariño
Jazmin Qquellon
Francesca Vasquez
Jean Pierre Jiron
Sonia Flores
Karen Campos
author_sort Carlos F. Caceres
collection DOAJ
description Summary: Background: Ongoing implementation of HIV pre-exposure prophylaxis (PrEP) in Latin America should consider lessons learned from implementation projects such as ImPrEP (Brazil/Mexico/Peru, 2018–2021). In this analysis we assessed the effect of variables ascertained in early appointments on HIV seroconversion among ImPrEP participants. Methods: ImPrEP enrolled HIV-negative men who have sex with men and transgender women (MSM/TGW) aged 18+ years reporting recent condomless anal sex, anal sex with HIV-positive partners, transactional sex, or sexually transmitted infections (STI). Participants received a 30-day PrEP supply; at the 30-day visit and quarterly thereafter they completed behavioural assessments, underwent HIV testing, and received 3-month PrEP supplies if HIV-negative. PrEP adherence was measured using the medication possession ratio (MPR) at the 30-day visit. We used Cox's proportional hazards regression to examine the effect of our sociodemographic, behavioural, STI, and early PrEP care engagement variables of interest on time to HIV seroconversion. Findings: Compared to participants in Brazil, the hazard ratio for HIV seroconversion was higher among those in Peru (HR = 7.91, 95% CI: 4.74–13.20). Compared to participants aged ≥35 years, the HR for HIV seroconversion was higher for those aged 18–24 (aHR = 4.84, 95% CI: 2.55–9.17 and 25–34 (aHR = 2.43, 95% CI: 1.21–4.91). HIV seroconversion was also associated with transgender identity (aHR = 2.28, 95% CI: 1.12–4.66), transactional sex (aHR = 1.88, 95% CI: 1.18–2.99), receptive condomless anal sex (aHR = 2.42, 95% CI: 1.42–4.12), STI diagnosis (aHR = 1.93, 95% CI: 1.25–2.99), and a MPR < 0.6 (aHR = 2.64, 95% CI: 1.52–4.60). Interpretation: While moderate-high, HIV incidence among ImPrEP participants represented a considerable reduction from figures observed among MSM/TGW not using PrEP/PEP. Interventions to improve PrEP adherence are needed among new Latin American PrEP users, especially if baseline factors associated with seroconversion are present. Long-acting injectable PrEP can also become useful for this population. Funding: This study was funded by UNITAID.
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spelling doaj-art-47b8f84f89404720a79cf14a9ddac8382025-08-20T02:29:45ZengElsevierThe Lancet Regional Health. Americas2667-193X2025-06-014610109810.1016/j.lana.2025.101098Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demonstration study (ImPrEP)Research in contextCarlos F. Caceres0Heather Pines1Kelika A. Konda2Annick Borquez3Ronaldo Moreira4Iuri Leite5Pedro Amparo6Marcelo Cunha7Thiago S. Torres8Juan V. Guanira9Jean-Pierre Jirón10Brenda Hoagland11Heleen Vermandere12Marcos Benedetti13Hamid Vega14Carlos M. Benites15Cristina Pimenta16Beatriz Grinztejn17Valdiléa Veloso18J. David Urbaez-BritoPolyana d’AlbuquerqueClaudio PalomboPaulo Ricardo AlencastroRaquel Keiko de Luca ItoJoão L. BenedettiFabio V. MariaPaula M. LuzLucilene FreitasKim GeraldoMonica DerricoSandro NazerTania KristicRenato GiradeRenato LimaAntônio R. CarvalhoCarla RochaPedro LeiteMarcio LessaMarilia Santini-OliveiraDaniel R.B. BezerraCleo de Oliveira SouzaJacinto CorrêaMarcelo AlvesCarolina SouzaCamilla PortugalMônica dos Santos ValõesGabriel Lima MotaJoyce Alves GomesCynthia Ferreira Lima FalcãoFernanda Falcão RibersonLuciano MeloTalita Andrade OliveiraAgnaldo Moreira Oliveira JúniorBruna FonsecaLeonor Henriette LannoyLudymilla Anderson Santiago CarlosJoão Paulo CunhaSonia Maria de Alencastro CoraciniThiago Oliveira RodriguesEmília Regina Scharf MettrauKelly Vieira MeiraHeder TavaresAna Paula Nunes Viveiros ValeirasTaiane Miyake Alves de Carvalho RochaAlex AmorimPatrícia SabadiniLuiz Gustavo CórdobaCaio GusmãoErika FaustinoJulia Soares da Silva HansenAgatha Mirian CunhaNeuza Uchiyama NishimuraJaime Eduardo Flygare Razo Prereira SantosAline Barnabé CanoWillyam Magnum Telles DiasMagô TonhonTania Regina RezendeAlex GomesEloá dos Santos RodriguesMaria das Dores Aires CarneiroAlexandre CastilhoMariana CarvalhoDulce Diaz-SosaCentli Guillen-Diaz-BarrigaLorena HernándezRebeca RoblesMaria Elena Medina-MoraMarcela GonzálezIvonne Huerta IceloAraczy Martinez DavalosJosé Gomez CastroLuis Obed Ocampo ValdezFernanda Ramírez BarajasVerónica Ruiz GonzálezGalileo Vargas GuadarramaIsrael MacíasJehovani Tena SánchezJuan Pablo Osuna NoriegaH. Rodrigo Moheno MJorge M. Bernal RamírezVíctor Dante Galicia JuarezGerardo VizcaínoFrancisco Javier ArjonaGino CalvoSilver VargasOliver ElorreagaXimena GutierrezFernando OlivosDamaris CaviedesDaniella AdriazolaEduardo JuárezGabriela MariñoJazmin QquellonFrancesca VasquezJean Pierre JironSonia FloresKaren CamposUniversidad Peruana Cayetano Heredia, Center for Interdisciplinary Studies in Sexuality, AIDS and Society, Lima, Peru; Corresponding author. Av. Armendáriz 445, Miraflores, Lima, 15074, Peru.San Diego State University, San Diego, CA, USAUniversidad Peruana Cayetano Heredia, Center for Interdisciplinary Studies in Sexuality, AIDS and Society, Lima, Peru; University of Southern California, Los Angeles, CA, USAUniversity of California, San Diego, CA, USAOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilUniversidad Peruana Cayetano Heredia, Center for Interdisciplinary Studies in Sexuality, AIDS and Society, Lima, PeruUniversidad Peruana Cayetano Heredia, Center for Interdisciplinary Studies in Sexuality, AIDS and Society, Lima, PeruOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilNational Institute of Public Health, Cuernavaca, MexicoOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City, MexicoMinistry of Health of Peru, Lima, PeruMinistry of Health of Brazil, Brasilia, BrazilOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilOswaldo Cruz Foundation/Fiocruz, Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, BrazilSummary: Background: Ongoing implementation of HIV pre-exposure prophylaxis (PrEP) in Latin America should consider lessons learned from implementation projects such as ImPrEP (Brazil/Mexico/Peru, 2018–2021). In this analysis we assessed the effect of variables ascertained in early appointments on HIV seroconversion among ImPrEP participants. Methods: ImPrEP enrolled HIV-negative men who have sex with men and transgender women (MSM/TGW) aged 18+ years reporting recent condomless anal sex, anal sex with HIV-positive partners, transactional sex, or sexually transmitted infections (STI). Participants received a 30-day PrEP supply; at the 30-day visit and quarterly thereafter they completed behavioural assessments, underwent HIV testing, and received 3-month PrEP supplies if HIV-negative. PrEP adherence was measured using the medication possession ratio (MPR) at the 30-day visit. We used Cox's proportional hazards regression to examine the effect of our sociodemographic, behavioural, STI, and early PrEP care engagement variables of interest on time to HIV seroconversion. Findings: Compared to participants in Brazil, the hazard ratio for HIV seroconversion was higher among those in Peru (HR = 7.91, 95% CI: 4.74–13.20). Compared to participants aged ≥35 years, the HR for HIV seroconversion was higher for those aged 18–24 (aHR = 4.84, 95% CI: 2.55–9.17 and 25–34 (aHR = 2.43, 95% CI: 1.21–4.91). HIV seroconversion was also associated with transgender identity (aHR = 2.28, 95% CI: 1.12–4.66), transactional sex (aHR = 1.88, 95% CI: 1.18–2.99), receptive condomless anal sex (aHR = 2.42, 95% CI: 1.42–4.12), STI diagnosis (aHR = 1.93, 95% CI: 1.25–2.99), and a MPR < 0.6 (aHR = 2.64, 95% CI: 1.52–4.60). Interpretation: While moderate-high, HIV incidence among ImPrEP participants represented a considerable reduction from figures observed among MSM/TGW not using PrEP/PEP. Interventions to improve PrEP adherence are needed among new Latin American PrEP users, especially if baseline factors associated with seroconversion are present. Long-acting injectable PrEP can also become useful for this population. Funding: This study was funded by UNITAID.http://www.sciencedirect.com/science/article/pii/S2667193X25001085Pre-exposure prophylaxisHIV seroconversionHIV seroincidenceSexual and gender minoritiesMedication adherenceLatin America
spellingShingle Carlos F. Caceres
Heather Pines
Kelika A. Konda
Annick Borquez
Ronaldo Moreira
Iuri Leite
Pedro Amparo
Marcelo Cunha
Thiago S. Torres
Juan V. Guanira
Jean-Pierre Jirón
Brenda Hoagland
Heleen Vermandere
Marcos Benedetti
Hamid Vega
Carlos M. Benites
Cristina Pimenta
Beatriz Grinztejn
Valdiléa Veloso
J. David Urbaez-Brito
Polyana d’Albuquerque
Claudio Palombo
Paulo Ricardo Alencastro
Raquel Keiko de Luca Ito
João L. Benedetti
Fabio V. Maria
Paula M. Luz
Lucilene Freitas
Kim Geraldo
Monica Derrico
Sandro Nazer
Tania Kristic
Renato Girade
Renato Lima
Antônio R. Carvalho
Carla Rocha
Pedro Leite
Marcio Lessa
Marilia Santini-Oliveira
Daniel R.B. Bezerra
Cleo de Oliveira Souza
Jacinto Corrêa
Marcelo Alves
Carolina Souza
Camilla Portugal
Mônica dos Santos Valões
Gabriel Lima Mota
Joyce Alves Gomes
Cynthia Ferreira Lima Falcão
Fernanda Falcão Riberson
Luciano Melo
Talita Andrade Oliveira
Agnaldo Moreira Oliveira Júnior
Bruna Fonseca
Leonor Henriette Lannoy
Ludymilla Anderson Santiago Carlos
João Paulo Cunha
Sonia Maria de Alencastro Coracini
Thiago Oliveira Rodrigues
Emília Regina Scharf Mettrau
Kelly Vieira Meira
Heder Tavares
Ana Paula Nunes Viveiros Valeiras
Taiane Miyake Alves de Carvalho Rocha
Alex Amorim
Patrícia Sabadini
Luiz Gustavo Córdoba
Caio Gusmão
Erika Faustino
Julia Soares da Silva Hansen
Agatha Mirian Cunha
Neuza Uchiyama Nishimura
Jaime Eduardo Flygare Razo Prereira Santos
Aline Barnabé Cano
Willyam Magnum Telles Dias
Magô Tonhon
Tania Regina Rezende
Alex Gomes
Eloá dos Santos Rodrigues
Maria das Dores Aires Carneiro
Alexandre Castilho
Mariana Carvalho
Dulce Diaz-Sosa
Centli Guillen-Diaz-Barriga
Lorena Hernández
Rebeca Robles
Maria Elena Medina-Mora
Marcela González
Ivonne Huerta Icelo
Araczy Martinez Davalos
José Gomez Castro
Luis Obed Ocampo Valdez
Fernanda Ramírez Barajas
Verónica Ruiz González
Galileo Vargas Guadarrama
Israel Macías
Jehovani Tena Sánchez
Juan Pablo Osuna Noriega
H. Rodrigo Moheno M
Jorge M. Bernal Ramírez
Víctor Dante Galicia Juarez
Gerardo Vizcaíno
Francisco Javier Arjona
Gino Calvo
Silver Vargas
Oliver Elorreaga
Ximena Gutierrez
Fernando Olivos
Damaris Caviedes
Daniella Adriazola
Eduardo Juárez
Gabriela Mariño
Jazmin Qquellon
Francesca Vasquez
Jean Pierre Jiron
Sonia Flores
Karen Campos
Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demonstration study (ImPrEP)Research in context
The Lancet Regional Health. Americas
Pre-exposure prophylaxis
HIV seroconversion
HIV seroincidence
Sexual and gender minorities
Medication adherence
Latin America
title Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demonstration study (ImPrEP)Research in context
title_full Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demonstration study (ImPrEP)Research in context
title_fullStr Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demonstration study (ImPrEP)Research in context
title_full_unstemmed Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demonstration study (ImPrEP)Research in context
title_short Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demonstration study (ImPrEP)Research in context
title_sort baseline variables associated with subsequent hiv seroconversion among gay bisexual and other men who have sex with men and transgender women a prospective multicenter prep demonstration study imprep research in context
topic Pre-exposure prophylaxis
HIV seroconversion
HIV seroincidence
Sexual and gender minorities
Medication adherence
Latin America
url http://www.sciencedirect.com/science/article/pii/S2667193X25001085
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AT claudiopalombo baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT pauloricardoalencastro baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT raquelkeikodelucaito baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT joaolbenedetti baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT fabiovmaria baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT paulamluz baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT lucilenefreitas baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT kimgeraldo baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT monicaderrico baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT sandronazer baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT taniakristic baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT renatogirade baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT renatolima baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT antoniorcarvalho baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT carlarocha baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT pedroleite baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT marciolessa baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT mariliasantinioliveira baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT danielrbbezerra baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT cleodeoliveirasouza baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT jacintocorrea baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT marceloalves baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT carolinasouza baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT camillaportugal baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT monicadossantosvaloes baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT gabriellimamota baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT joycealvesgomes baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT cynthiaferreiralimafalcao baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT fernandafalcaoriberson baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT lucianomelo baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT talitaandradeoliveira baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT agnaldomoreiraoliveirajunior baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT brunafonseca baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT leonorhenriettelannoy baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT ludymillaandersonsantiagocarlos baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT joaopaulocunha baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT soniamariadealencastrocoracini baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT thiagooliveirarodrigues baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT emiliareginascharfmettrau baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT kellyvieirameira baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT hedertavares baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT anapaulanunesviveirosvaleiras baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT taianemiyakealvesdecarvalhorocha baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT alexamorim baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT patriciasabadini baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT luizgustavocordoba baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT caiogusmao baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT erikafaustino baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT juliasoaresdasilvahansen baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT agathamiriancunha baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT neuzauchiyamanishimura baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT jaimeeduardoflygarerazoprereirasantos baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT alinebarnabecano baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT willyammagnumtellesdias baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT magotonhon baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT taniareginarezende baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT alexgomes baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT eloadossantosrodrigues baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT mariadasdoresairescarneiro baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT alexandrecastilho baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT marianacarvalho baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT dulcediazsosa baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT centliguillendiazbarriga baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT lorenahernandez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT rebecarobles baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT mariaelenamedinamora baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT marcelagonzalez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT ivonnehuertaicelo baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT araczymartinezdavalos baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT josegomezcastro baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT luisobedocampovaldez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT fernandaramirezbarajas baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT veronicaruizgonzalez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT galileovargasguadarrama baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT israelmacias baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT jehovanitenasanchez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT juanpabloosunanoriega baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT hrodrigomohenom baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT jorgembernalramirez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT victordantegaliciajuarez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT gerardovizcaino baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT franciscojavierarjona baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT ginocalvo baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT silvervargas baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT oliverelorreaga baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT ximenagutierrez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT fernandoolivos baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT damariscaviedes baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT daniellaadriazola baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT eduardojuarez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT gabrielamarino baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT jazminqquellon baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT francescavasquez baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT jeanpierrejiron baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT soniaflores baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext
AT karencampos baselinevariablesassociatedwithsubsequenthivseroconversionamonggaybisexualandothermenwhohavesexwithmenandtransgenderwomenaprospectivemulticenterprepdemonstrationstudyimprepresearchincontext