Potential role of hypobaric hypoxia environment in treating pan-cancer

Potential role of hypobaric hypoxia environment in treating pan-cancer

Abstract Cancer incidence and mortality are lower among high-altitude residents, suggesting that hypobaric hypoxia (HH) might protect against cancer. Our study aimed to develop a pan-cancer prognosis risk model using ADME genes, which are influenced by low oxygen, to explore HH’s impact on overall s...

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Bibliographic Details
Main Authors: Shixuan Zhang, Xiaoxi Hu, Mengzhen Sun, Xinrui Chen, Shiguan Le, Xilu Wang, Jiucun Wang, Zixin Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Hypobaric hypoxia environment
Pan-cancer
Drug targets
ADME genes
Survival analysis
Online Access:https://doi.org/10.1038/s41598-024-84561-3
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