Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort study
Objective The study aimed to compare the effectiveness and safety of ultrasound-guided microwave ablation (MWA) and percutaneous sclerotherapy (PS) for the treatment of large hepatic hemangioma (LHH).Methods This retrospective study included 96 patients who underwent MWA (n = 54) and PS (n = 42) as...
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Taylor & Francis Group
2024-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2023.2285705 |
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| author | Qian Cai Tong-Gang Qian Qi-Yu Zhao Shun-You Feng Qiao Yang Yan-Chun Luo Yu-Qing Dai Ping Liang Xiao-ling Yu Fang-Yi Liu Zhi-Yu Han Qiao-Wei Du Xin Li Jie Yu |
| author_facet | Qian Cai Tong-Gang Qian Qi-Yu Zhao Shun-You Feng Qiao Yang Yan-Chun Luo Yu-Qing Dai Ping Liang Xiao-ling Yu Fang-Yi Liu Zhi-Yu Han Qiao-Wei Du Xin Li Jie Yu |
| author_sort | Qian Cai |
| collection | DOAJ |
| description | Objective The study aimed to compare the effectiveness and safety of ultrasound-guided microwave ablation (MWA) and percutaneous sclerotherapy (PS) for the treatment of large hepatic hemangioma (LHH).Methods This retrospective study included 96 patients who underwent MWA (n = 54) and PS (n = 42) as first-line treatment for LHH in three tertiary hospitals from January 2016 to December 2021. Primary outcomes were technique efficacy rate (volume reduction rate [VRR] > 50% at 12 months), symptom relief rate at 12 months and local tumor progression (LTP). Secondary outcomes included procedure time, major complications, treatment sessions, cost and one-, two-, three-year VRR.Results During a median follow-up of 36 months, the MWA group showed a higher technique efficacy rate (100% vs. 90.4%, p = .018) and symptom relief rate (100% vs. 80%, p = .123) than the PS group. The MWA group had fewer treatment sessions, higher one-, two- and three-year VRR, lower LTP rate (all p < .05), longer procedure time and higher treatment costs than the PS group (both p < .001). MWA shared a comparable major complications rate (1.8% vs. 2.4%, p = .432) with PS. After multivariate analysis, the lesion’s heterogeneity and maximum diameter >8.1 cm were independent risk factors for LTP (all p < .05). In the PS group, lesions with a cumulative dose of bleomycin > 0.115 mg/cm3 had a lower risk of LTP (p = .006).Conclusions Both MWA and PS treatments for large hepatic hemangioma are safe and effective, with MWA being superior in terms of efficacy. |
| format | Article |
| id | doaj-art-47a7ddf81e3c49df9ae58800996fd6e9 |
| institution | Kabale University |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj-art-47a7ddf81e3c49df9ae58800996fd6e92025-01-03T09:30:27ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572024-12-0141110.1080/02656736.2023.2285705Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort studyQian Cai0Tong-Gang Qian1Qi-Yu Zhao2Shun-You Feng3Qiao Yang4Yan-Chun Luo5Yu-Qing Dai6Ping Liang7Xiao-ling Yu8Fang-Yi Liu9Zhi-Yu Han10Qiao-Wei Du11Xin Li12Jie Yu13Department of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Ultrasound, Zunhua People’s Hospital, Zunhua, ChinaDepartment of Ultrasound, Zhejiang University School of Medicine & the First Hospital of Zhejiang Province, Hangzhou, ChinaDepartment of Ultrasound, Zunhua People’s Hospital, Zunhua, ChinaDepartment of Ultrasound, Zunhua People’s Hospital, Zunhua, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital & Chinese PLA Medical College, Beijing, ChinaObjective The study aimed to compare the effectiveness and safety of ultrasound-guided microwave ablation (MWA) and percutaneous sclerotherapy (PS) for the treatment of large hepatic hemangioma (LHH).Methods This retrospective study included 96 patients who underwent MWA (n = 54) and PS (n = 42) as first-line treatment for LHH in three tertiary hospitals from January 2016 to December 2021. Primary outcomes were technique efficacy rate (volume reduction rate [VRR] > 50% at 12 months), symptom relief rate at 12 months and local tumor progression (LTP). Secondary outcomes included procedure time, major complications, treatment sessions, cost and one-, two-, three-year VRR.Results During a median follow-up of 36 months, the MWA group showed a higher technique efficacy rate (100% vs. 90.4%, p = .018) and symptom relief rate (100% vs. 80%, p = .123) than the PS group. The MWA group had fewer treatment sessions, higher one-, two- and three-year VRR, lower LTP rate (all p < .05), longer procedure time and higher treatment costs than the PS group (both p < .001). MWA shared a comparable major complications rate (1.8% vs. 2.4%, p = .432) with PS. After multivariate analysis, the lesion’s heterogeneity and maximum diameter >8.1 cm were independent risk factors for LTP (all p < .05). In the PS group, lesions with a cumulative dose of bleomycin > 0.115 mg/cm3 had a lower risk of LTP (p = .006).Conclusions Both MWA and PS treatments for large hepatic hemangioma are safe and effective, with MWA being superior in terms of efficacy.https://www.tandfonline.com/doi/10.1080/02656736.2023.2285705Hemangiomaultrasonographyablation techniquesmicrowavessclerotherapy |
| spellingShingle | Qian Cai Tong-Gang Qian Qi-Yu Zhao Shun-You Feng Qiao Yang Yan-Chun Luo Yu-Qing Dai Ping Liang Xiao-ling Yu Fang-Yi Liu Zhi-Yu Han Qiao-Wei Du Xin Li Jie Yu Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort study International Journal of Hyperthermia Hemangioma ultrasonography ablation techniques microwaves sclerotherapy |
| title | Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort study |
| title_full | Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort study |
| title_fullStr | Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort study |
| title_full_unstemmed | Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort study |
| title_short | Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort study |
| title_sort | percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma a multi center cohort study |
| topic | Hemangioma ultrasonography ablation techniques microwaves sclerotherapy |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2023.2285705 |
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