Targeting SETDB1 in cancer and immune regulation: Potential therapeutic strategies in cancer
Abstract SET domain bifurcated histone lysine methyltransferase 1 (SETDB1/ESET), a pivotal H3K9 methyltransferase, has been extensively studied since its discovery over two decades ago. SETDB1 plays critical roles in immune regulation, including B cell maturation, T‐cell activity modulation, and end...
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| Main Authors: | Bo‐Syong Pan, Cheng‐Yu Lin, Gilbert Aaron Lee, Hui‐Kuan Lin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-03-01
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| Series: | Kaohsiung Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/kjm2.12933 |
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