Features of expression of protein Claudin 11 at various forms of male infertility
Abstract Immunohistochemical features of an expression of protein Claudin 11 in testicular tissue of 28 patients with excretory-obstructive and secretory forms of male infertility are studied. Significant decrease of protein Claudin 11 IHC expression level at the secretory form of male inferti...
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| Format: | Article |
| Language: | English |
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Zaporizhzhia State Medical and Pharmaceutical University
2012-12-01
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| Series: | Patologìâ |
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| Online Access: | http://pat.zsmu.edu.ua/article/view/16986/14676 |
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| author | S. V. Bazalytska A.M. Romanenko Yu. V. Persidsky |
| author_facet | S. V. Bazalytska A.M. Romanenko Yu. V. Persidsky |
| author_sort | S. V. Bazalytska |
| collection | DOAJ |
| description | Abstract
Immunohistochemical features of an expression of protein Claudin 11 in testicular tissue of 28 patients with excretory-obstructive and secretory forms of male infertility are studied. Significant decrease of protein Claudin 11 IHC expression level at the secretory form of male infertility and at syndrome «only Sertoli cells» is revealed in comparison with excretory-obstructive form of male infertility. Results testify to considerable disturbances of blood-testis barrier, which have become the basis of the development of additional immune component and intensification of pathological changes in patients with the secretory form of male infertility. |
| format | Article |
| id | doaj-art-479a0fdd96a346779a1975e43c5d1a76 |
| institution | OA Journals |
| issn | 2306-8027 2310-1237 |
| language | English |
| publishDate | 2012-12-01 |
| publisher | Zaporizhzhia State Medical and Pharmaceutical University |
| record_format | Article |
| series | Patologìâ |
| spelling | doaj-art-479a0fdd96a346779a1975e43c5d1a762025-08-20T02:37:55ZengZaporizhzhia State Medical and Pharmaceutical UniversityPatologìâ2306-80272310-12372012-12-013111410.14739/2310-1237.2012.3.16986Features of expression of protein Claudin 11 at various forms of male infertilityS. V. BazalytskaA.M. RomanenkoYu. V. PersidskyAbstract Immunohistochemical features of an expression of protein Claudin 11 in testicular tissue of 28 patients with excretory-obstructive and secretory forms of male infertility are studied. Significant decrease of protein Claudin 11 IHC expression level at the secretory form of male infertility and at syndrome «only Sertoli cells» is revealed in comparison with excretory-obstructive form of male infertility. Results testify to considerable disturbances of blood-testis barrier, which have become the basis of the development of additional immune component and intensification of pathological changes in patients with the secretory form of male infertility.http://pat.zsmu.edu.ua/article/view/16986/14676male infertilityprotein Claudin 11 |
| spellingShingle | S. V. Bazalytska A.M. Romanenko Yu. V. Persidsky Features of expression of protein Claudin 11 at various forms of male infertility Patologìâ male infertility protein Claudin 11 |
| title | Features of expression of protein Claudin 11 at various forms of male infertility |
| title_full | Features of expression of protein Claudin 11 at various forms of male infertility |
| title_fullStr | Features of expression of protein Claudin 11 at various forms of male infertility |
| title_full_unstemmed | Features of expression of protein Claudin 11 at various forms of male infertility |
| title_short | Features of expression of protein Claudin 11 at various forms of male infertility |
| title_sort | features of expression of protein claudin 11 at various forms of male infertility |
| topic | male infertility protein Claudin 11 |
| url | http://pat.zsmu.edu.ua/article/view/16986/14676 |
| work_keys_str_mv | AT svbazalytska featuresofexpressionofproteinclaudin11atvariousformsofmaleinfertility AT amromanenko featuresofexpressionofproteinclaudin11atvariousformsofmaleinfertility AT yuvpersidsky featuresofexpressionofproteinclaudin11atvariousformsofmaleinfertility |