Osthole: A Coumarin with Dual Roles in Biology and Chemistry
Osthole is a natural coumarin-like compound isolated from the <i>Fructus cnidii</i>. In the last few years, this plant-derived product and its derivatives have aroused much attention for their interesting biological activities, including anticancer, anti-inflammatory, neuroprotective, an...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-05-01
|
| Series: | Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-7737/14/6/588 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Osthole is a natural coumarin-like compound isolated from the <i>Fructus cnidii</i>. In the last few years, this plant-derived product and its derivatives have aroused much attention for their interesting biological activities, including anticancer, anti-inflammatory, neuroprotective, and insecticidal effects. This review summarizes the recent progress on the biological activities of osthole and its derivatives from 2018 to early 2025, with a focus on their total synthesis, structural modifications, and mechanisms of action. Additionally, structure–activity relationships (SARs) of osthole derivatives are presented. This review aims to serve as a comprehensive reference for future research on osthole and its derivatives in both medicinal and agricultural applications. |
|---|---|
| ISSN: | 2079-7737 |