Analysis of LINE-1 DNA Methylation in Colorectal Cancer, Precancerous Lesions, and Adjacent Normal Mucosa

Analysis of LINE-1 DNA Methylation in Colorectal Cancer, Precancerous Lesions, and Adjacent Normal Mucosa

<i>Background and Objectives</i>: Colorectal cancer (CRC) is a major cause of cancer morbidity and mortality worldwide. Genetic and epigenetic changes, especially DNA methylation alterations, are key in CRC development. <i>LINE-1</i> hypomethylation marks global DNA methylati...

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Bibliographic Details
Main Authors: Inga Kildusiene, Ryte Rynkeviciene, Auguste Kaceniene, Rima Miknaite, Kestutis Suziedelis, Giedre Smailyte
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Medicina
Subjects:
<i>LINE-1</i>
colorectal cancer
methylation
Online Access:https://www.mdpi.com/1648-9144/61/7/1243
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