Activation of Sirt1 protects from single-walled carbon nanotubes-induced pulmonary fibrosis by inhibiting alveolar macrophage senescence

Activation of Sirt1 protects from single-walled carbon nanotubes-induced pulmonary fibrosis by inhibiting alveolar macrophage senescence

Purpose: Expanding industrial applications of carbon nanotube (CNT) have led to the concern for the increased risk of pulmonary fibrosis. The current study investigated the role of alveolar macrophages (AMs) senescence during single-walled CNT (SWCNT)-provoked pulmonary fibrosis and the underlying m...

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Bibliographic Details
Main Authors: Xiang Zhang, Wenrui Zhao, Xinxin Hu, Yalu Shen, Yu Gan, Jiayang Zou, Yunfei Zhou, Tingting Zhu, Tong Shen
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Carbon nanotube
Silent information regulator 1
Alveolar macrophage
Senescence
Pulmonary fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325009741
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