Complement Activation is More Pronounced in the Kidneys of Critically Ill Patients With COVID-19 Than in Those With Bacterial Sepsis

Complement Activation is More Pronounced in the Kidneys of Critically Ill Patients With COVID-19 Than in Those With Bacterial Sepsis

Introduction: Previous studies have shown that the complement system plays an important role in COVID-19 acute kidney injury (AKI). However, studies evaluating the activation pathways in vivo are scarce and have shown contradictory findings. It has also been suggested that COVID-19 AKI has a pathoph...

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Bibliographic Details
Main Authors: Firas F. Alkaff, Grietje G. Talen, Marius C. van den Heuvel, Meint Volbeda, Matijs van Meurs, Jill Moser, Mohamed R. Daha, Jacob van den Born, Stefan P. Berger
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Kidney International Reports
Subjects:
acute kidney injury
complement
COVID-19
kidney
sepsis
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925002529
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