Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor

Background: Accumulating evidence suggests that the receptor binding domain (RBD) of the SARS-CoV-2 Omicron variant has several times more binding affinity to the human angiotensin-converting enzyme 2 (ACE2) receptor compared to the RBD of the original Covid-19 strain. This increased binding affinit...

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Bibliographic Details
Main Authors: Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Phytomedicine Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667031324001799
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