The ADAMTS2 metalloproteinase inhibits tumor growth by regulating the innate immune system

The ADAMTS2 metalloproteinase inhibits tumor growth by regulating the innate immune system

Abstract Background ADAMTS2 is a metalloproteinase known to be implicated in collagen maturation and regulation of (lymph)angiogenesis. As these properties are likely to alter tumor progression, we aimed to assess the overall impact of ADAMTS2 on cancer development. Methods and results Using publicl...

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Main Authors: Loïc Joannes, Laura Dupont, Louis Stock, Esther Arpigny, Pascale Hubert, Marie Ancion, Margaux Luyckx, Joan Abinet, Wen Peng, Didier Calaldo, Agnes Noel, Thomas Marichal, Michael Herfs, Christophe Deroanne, Alain Colige
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
Subjects:
ADAMTS
IMMUNITY
Tumor micro-environment
Online Access:https://doi.org/10.1186/s12935-025-03880-1
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